Protein Alignment scro and Hoxb3

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_034588.2
• Gene: Hoxb3 / 15410
• MGIID: 96184
• Length: 433
• Species: Mus musculus
• Alignment Length: 438
• Identity: 103/438 - (23%)
• Similarity: 155/438 - (35%)
• Gaps: 122/438 - (27%)

  Fly    95 HLQNLHSQHQSTLFNSNHSTPFSVTDILSPIEESYRKLELNGN------PPSPFRSNSSSSSINS 153
            ||:..:.:...:|.:..::.|.:            :..||||:      .|.|..:...|...::
Mouse    42 HLEGDYQRSACSLQSLGNAAPHA------------KSKELNGSCMRPGLAPEPLPAPPGSPPPSA 94

  Fly   154 PGTLTTSTMAN---PYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAIS 215
            ..|.|||...|   |...|        ...||...|.:|.      :....|...:....:
Mouse    95 APTSTTSNSNNGGGPSKSG--------PPKCGAGSNSTLT------KQIFPWMKESRQTSK---- 141

  Fly   216 RLMSSSASGTMSHMG----------------NMSGLAACSVSDSKPLQFPLAQRRKR-RVLFTQA 263
              :.:|:.||....|                :..|.......|..|   |.:...|| |..:|.|
Mouse   142 --LKNSSPGTAEGCGGGGGGGGGGGGGGGGSSGGGGGGGGGGDKSP---PGSAASKRARTAYTSA 201

  Fly   264 QVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPAS 328
            |:.|||:.|...|||..|.|..:|:|::|:..|:||||||.|.|.|:..|.|.:|..:....||.
Mouse   202 QLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAG 266

  Fly   329 SPRRVAVPVLVKDGKPCSG--NNSSSQSQQHGTNSTSAGNNTGSANNGNANSGIVSVTANVSGGL 391
            ||.:   |:     :..:|  |...|.:..:.:.|..|        .|..:....::.:|....|
Mouse   267 SPPQ---PM-----QSTAGFMNALHSMTPSYDSPSPPA--------FGKGHQNAYALPSNYQPPL 315

  Fly   392 NLITG-DAPNSHSPDTSSS-----LLA---SYGT---------VGGSNVA-MLQQPCNNTLMS-N 436
            .   | .||..:.|..:|.     |.|   :|||         |||...| .|..|...:|.. |
Mouse   316 K---GCGAPQKYPPTPASEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLN 377

  Fly   437 SLAMAYRNQNNFISNG--------HQQQC----------GGYLPLQGR 466
            .|  ::....|...||        |...|          ..:.|.|||
Mouse   378 HL--SHHPSGNLDYNGAAPMGPNQHHGPCDPHPTYTDLSSHHAPPQGR 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	27/56 (48%)
Hoxb3	NP_034588.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..124		17/80 (21%)
		Antp-type hexapeptide	129..134		1/4 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..195		10/67 (15%)
		Homeodomain	192..248	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..276		8/34 (24%)
		DUF4074	369..431	CDD:463833	12/57 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..433		8/35 (23%)