Protein Alignment scro and Hmx1

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_034575.1
• Gene: Hmx1 / 15371
• MGIID: 107178
• Length: 332
• Species: Mus musculus
• Alignment Length: 250
• Identity: 70/250 - (28%)
• Similarity: 103/250 - (41%)
• Gaps: 76/250 - (30%)

  Fly   126 EESYRKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMGTLYHSPGVQTYCGPTDNL--S 188
            |...|.|.|...||.            .||.        |:|:|           ||.|...  .
Mouse    79 EARARALGLGPRPPP------------GPGP--------PFALG-----------CGGTTRWYPR 112

  Fly   189 LAGHY-------TDMRNS-----------ASWYGSTANDPRF----AISRLMSSSASGT----MS 227
            :.|.|       |..|:|           ::|       ||.    .:.|.:::....|    .:
Mouse   113 VHGGYGGGLSPDTSDRDSPETGEEMGRAESAW-------PRCPGPGTVPREVTTQGPATGGEEAA 170

  Fly   228 HMGNMSGLAACSVSDSKPLQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHL 292
            .:.....:||.:..:::.     .:|:|.|.:|:::||::||..|..:||||:.||..||:.:.|
Mouse   171 ELAEAPAVAAAATGEARG-----GRRKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQL 230

  Fly   293 TPTQVKIWFQNHRYKCKRQ-AKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKPCS 346
            |.|||||||||.|.|.||| |.|...|..:    |..:.|.|.||||..:..|.:
Mouse   231 TETQVKIWFQNRRNKWKRQLAAELEAASLS----PPGAQRLVRVPVLYHESPPAA 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	29/55 (53%)
Hmx1	NP_034575.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	28..170		24/128 (19%)
		Homeodomain	192..248	CDD:459649	29/55 (53%)
		HMX family specific domain 1	251..261		3/13 (23%)
		HMX family specific domain 2	264..277		6/12 (50%)