Protein Alignment scro and Hlx

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_032276.1
• Gene: Hlx / 15284
• MGIID: 96109
• Length: 476
• Species: Mus musculus
• Alignment Length: 425
• Identity: 102/425 - (24%)
• Similarity: 169/425 - (39%)
• Gaps: 122/425 - (28%)

  Fly    78 AAAAAVAHHHHNLSSIHHLQNLHSQHQSTLFNSNHSTP-FSVTDI-------LSPIEESY----- 129
            |:||..||    |.|:|.    |:..|:...:....|| .:.:::       |||:..::
Mouse    67 ASAALTAH----LGSVHP----HASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAFHQHLP 123

  Fly   130 -----RKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMG------------------TL 171
                 ::.:....||.|.|    :.|:..|   |:.|...|:..|                  :.
Mouse   124 QQSPTQQQQPQQQPPPPPR----AVSLQPP---TSGTRVVPHHSGSAPAPSSKDLKFGIDRILSA 181

  Fly   172 YHSPGVQTYCGPTDNLSL------AG-HYTDMRNSASWYGSTANDP---RFAISRLMSSSASGTM 226
            ...|.|:......|..||      || |...::.||..:.::. ||   ..||...:||:...::
Mouse   182 EFDPKVKEGNTLRDLTSLLTGGRPAGVHLAGLQPSAGQFFASL-DPISEASAILSPLSSNPRNSV 245

  Fly   227 SH--MGNMSGLAACSVSDSKPLQFPLAQRRKR---RVLFTQAQVYELERRFKQQRYLSAPEREHL 286
            .|  .....|..|....|:.|..:    :|||   |.:|:..|...||:||:.|:|::.|:|:.|
Mouse   246 QHQFQDTFPGPYAVLTKDTMPQTY----KRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQL 306

  Fly   287 ASLIHLTPTQVKIWFQNHRYKCK-------RQAKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKP 344
            |:::.||..|||:||||.|.|.:       ::.|:|...|:.....||...|....|.. .:|:
Mouse   307 AAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGVPAEGEREERSPSR-SEGE- 369

  Fly   345 CSGNNSSSQS---------QQHGT----------------------NSTSAG----NNTGSANNG 374
            ....:|.|:|         :..||                      :|||..    ::|.|..:|
Mouse   370 AESESSDSESLDMAPSDTERTEGTERSLHQTTVIKASAAGALITASSSTSGSSFSFSSTSSLGSG 434

  Fly   375 NANSGIVSVTANVSGGLNLITGDAPNSHSPDTSSS 409
            |.:.|    :|:..||   ...:.|::|.|..:||
Mouse   435 NTHVG----SASSLGG---NCSELPSAHQPSVTSS 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	27/65 (42%)
Hlx	NP_032276.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..169		10/55 (18%)
		Homeodomain	270..330	CDD:459649	27/59 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..401		13/74 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..476		16/57 (28%)