Protein Alignment scro and Hhex

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_032271.1
• Gene: Hhex / 15242
• MGIID: 96086
• Length: 271
• Species: Mus musculus
• Alignment Length: 294
• Identity: 74/294 - (25%)
• Similarity: 115/294 - (39%)
• Gaps: 72/294 - (24%)

  Fly   107 LFNSNHSTPFSVTDILSPIEESYRKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMGTL 171
            |....|.|||.:.||            |...|.:|    :.:.::.||.:..||.:::
Mouse    24 LLQPAHPTPFYIDDI------------LGRGPAAP----TPTPTLPSPNSSFTSLVSS------- 65

  Fly   172 YHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASGTMSH--MGNMSG 234
            |.:|..:    ||.......|:.....:|::..|....|.:...|.::......:.|  :|
Mouse    66 YRTPVYE----PTPVHPAFSHHPAAALAAAYGPSGFGGPLYPFPRTVNDYTHALLRHDPLG---- 122

  Fly   235 LAACSVSDSKP------LQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLT 293
                     ||      ||.||.:|:..:|.|:..|..|||::|:.|:|||.|||:.||.::.|:
Mouse   123 ---------KPLLWSPFLQRPLHKRKGGQVRFSNDQTVELEKKFETQKYLSPPERKRLAKMLQLS 178

  Fly   294 PTQVKIWFQNHRYKCKRQAKEKAMA-------------EQNQ-----HNQPASSPRRVAVPVLVK 340
            ..|||.||||.|.|.:|..:|...:             ||.|     .|:.||..|....|
Mouse   179 ERQVKTWFQNRRAKWRRLKQENPQSNKKDALDSLDTSCEQGQDLPSEQNKGASLDRSQCSP---- 239

  Fly   341 DGKPCSGNNSSSQSQQHGTNSTSAGNNTGSANNG 374
              .|.|..:..|:..:..........:.|..|.|
Mouse   240 --SPASQEDPDSEISEDSDQEVDIEGDKGYFNAG 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	26/55 (47%)
Hhex	NP_032271.1	Interaction with SOX13. /evidence=ECO:0000250|UniProtKB:Q03014	1..138		31/153 (20%)
		Required for WNT signaling induction. /evidence=ECO:0000250|UniProtKB:Q03014	138..271		42/138 (30%)
		Homeodomain	143..195	CDD:459649	26/51 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..271		15/81 (19%)