Protein Alignment scro and Nkx6-2

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_899071.2
• Gene: Nkx6-2 / 14912
• MGIID: 1352738
• Length: 277
• Species: Mus musculus
• Alignment Length: 272
• Identity: 71/272 - (26%)
• Similarity: 102/272 - (37%)
• Gaps: 92/272 - (33%)

  Fly   114 TPFSVTDILS-PIEESYRKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMGTLYHSPGV 177
            ||..::|||. |:..:..  .|.|:.|   |.|..:||..                  :|..|..
Mouse    56 TPHGISDILGRPVGAAGG--GLLGSLP---RLNGLASSAG------------------VYFGPAA 97

  Fly   178 QTYCG-PTDNLSLAGHYTDMRNSASW----YGSTANDPRFAISRLMSSSASGTMSHMGNMSGLAA 237
            ....| |.....|.|     |....|    .||...|||.|    .|:.|.|.:...|
Mouse    98 AVARGYPKPLAELPG-----RPPIFWPGVVQGSPWRDPRLA----GSAQAGGVLDKDG------- 146

  Fly   238 CSVSDSKPLQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQ 302
                          :::..|..|:..|::.||:.|:|.:||:.|||..||..:.:|.:|||:|||
Mouse   147 --------------KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQ 197

  Fly   303 NHRYKC-KRQAKEKAMAEQNQ-------------------HNQPA---SSPRRVAVPVLVKDGK- 343
            |.|.|. ||.|.|.|.|::.|                   :|:|.   |...::.  .|:|..|
Mouse   198 NRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDEYNRPLDPNSDDEKIT--RLLKKHKP 260

  Fly   344 -------PCSGN 348
                   ||.|:
Mouse   261 SNLALVSPCGGS 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	24/56 (43%)
Nkx6-2	NP_899071.2	Homeodomain	147..205	CDD:459649	24/57 (42%)