Protein Alignment scro and NKX2-5

DIOPT Version :9

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_004378.1
• Gene: NKX2-5 / 1482
• HGNCID: 2488
• Length: 324
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 111/337 - (32%)
• Similarity: 151/337 - (44%)
• Gaps: 80/337 - (23%)

  Fly   114 TPFSVTDILSPIEESYRKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMGTLYHSPGVQ 178
            |||||.|||: :|:..|.|...|...:...:..:.||     .:..:.....|| |....:||:
Human    10 TPFSVKDILN-LEQQQRSLAAAGELSARLEATLAPSS-----CMLAAFKPEAYA-GPEAAAPGL- 66

  Fly   179 TYCGPTDNLSLAGHYTDMRNSASWYGST-------------ANDPRFAISRLMSSSASGTMSHMG 230
                |.....| |........||.:.:.             |.|||.....|.:
Human    67 ----PELRAEL-GRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCA----------- 115

  Fly   231 NMSGLAACSVSDSKPLQFPLAQRRKR-RVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTP 294
             :........:::...:.|.|:||:: ||||:||||||||||||||||||||||:.|||::.||.
Human   116 -LQKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTS 179

  Fly   295 TQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKPCSGNNSSSQSQQHGT 359
            |||||||||.|||||||.:::.:........|....||:||||||:|||||.| :|:..:..:|.
Human   180 TQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLG-DSAPYAPAYGV 243

  Fly   360 NSTSAGNN---------------------------------TGSANNGNANSGIVSVTANVSGGL 391
            .....|.|                                 |.:|||...|.|:..:.|..|.|:
Human   244 GLNPYGYNAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGI 308

  Fly   392 NLITGDAPNSHS 403
                   |.|:|
Human   309 -------PQSNS 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	43/53 (81%)
NKX2-5	NP_004378.1	Homeobox	145..194	CDD:278475	40/48 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143184
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740