Protein Alignment scro and DBX1

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001025036.2
• Gene: DBX1 / 120237
• HGNCID: 33185
• Length: 343
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 68/263 - (25%)
• Similarity: 106/263 - (40%)
• Gaps: 64/263 - (24%)

  Fly   114 TPFSVTDILSPIEESYRKLELNGNPPSPFRSNSSS-------SSINSPGTLTTSTMANPYAMGTL 171
            |....:|:.||...|.|    .|:||:.|...|.:       ::|.|.|..|.::.|       |
Human    75 TDTGASDLGSPGPGSRR----GGSPPTAFSPASETTFLKFGVNAILSSGPRTETSPA-------L 128

  Fly   172 YHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASGTMSHMGNMSGLA 236
            ..|...:|:..|    ...|.:.....|:.:..|::..|           ..||.|
Human   129 LQSVPPKTFAFP----YFEGSFQPFIRSSYFPASSSVVP-----------IPGTFS--------- 169

  Fly   237 ACSVSDSKPLQFPLAQRRK------RRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPT 295
                       :|||.|.|      ||.:|:..|...||:.|::|:|:|.|:|:.||:.:.|..:
Human   170 -----------WPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDS 223

  Fly   296 QVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKPCSGNNSSSQSQQHGTN 360
            ||||||||.|.|. |.:||:.:.......:.....:....|.|...|:...||    :.::.|..
Human   224 QVKIWFQNRRMKW-RNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGN----EEEEEGPG 283

  Fly   361 STS 363
            |.|
Human   284 SPS 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	26/61 (43%)
DBX1	NP_001025036.2	PRK12323	<49..182	CDD:481241	32/152 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..100		9/28 (32%)
		Homeodomain	184..238	CDD:459649	25/54 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..343		10/51 (20%)