Protein Alignment scro and Nkx2-5

DIOPT Version :9

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_446103.2
• Gene: Nkx2-5 / 114109
• RGDID: 620520
• Length: 319
• Species: Rattus norvegicus
• Alignment Length: 379
• Identity: 124/379 - (32%)
• Similarity: 164/379 - (43%)
• Gaps: 93/379 - (24%)

  Fly   114 TPFSVTDILSPIEESYR---------KLELNGNPPS----PFRSNS-SSSSINSPGTLTTSTMAN 164
            |||||.|||: :|:..|         :||....|.|    .|:..: |.....:||.........
  Rat    10 TPFSVKDILN-LEQQQRSLAAGDLSARLEATLAPASCMLAAFKPEAYSGPEAAAPGLAELRAELG 73

  Fly   165 PYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASGTMSHM 229
            |..      ||...:...||........|.|        ...|.|||.....|.:
  Rat    74 PAP------SPPKCSPAFPTAPTFYPRAYGD--------PDPAKDPRADKKELCA---------- 114

  Fly   230 GNMSGLAACSVSDSKPLQFPLAQRRKR-RVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLT 293
              :........:::...:.|.|:||:: ||||:||||||||||||||||||||||:.|||::.||
  Rat   115 --LQKAVELDKAETDGAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLT 177

  Fly   294 PTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKPCSGNNSSSQSQQHG 358
            .|||||||||.|||||||.:::.:........||   ||:||||||:|||||.| :|::.:..:|
  Rat   178 STQVKIWFQNRRYKCKRQRQDQTLELLGPPPPPA---RRIAVPVLVRDGKPCLG-DSAAYAPAYG 238

  Fly   359 TNSTSAGNNT------GSANNGNANSGIVSVTANVSGGLNLITGDAPNSHSPD--TSSSLLASYG 415
            ....:.|.|.      |.|....|.|...:..|            ||.:..|.  .::|...::|
  Rat   239 VGLNAYGYNAYPYPGYGGAACSPAYSCAAAYPA------------APPAAQPPAAAANSNFVNFG 291

  Fly   416 TVGGSNVAMLQQPCNNTLMSNSLAMAYRNQNNFISNGHQQQCGGYLPLQG-RAW 468
             ||..|.  :|.|                       |..|...|...|.| |||
  Rat   292 -VGDLNT--VQSP-----------------------GMPQGNSGVSTLHGIRAW 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	43/53 (81%)
Nkx2-5	NP_446103.2	Homeobox	144..194	CDD:395001	41/49 (84%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336904
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740