Protein Alignment scro and VAX1

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001106175.1
• Gene: VAX1 / 11023
• HGNCID: 12660
• Length: 334
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 75/299 - (25%)
• Similarity: 114/299 - (38%)
• Gaps: 55/299 - (18%)

  Fly   183 PTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASGTMSHMGNMSGLAACSVSDSKPLQ 247
            |....|.:|...|...|.|   ::|.||.:. .|::...|.|::..:....||
Human    47 PQGAFSASGAAEDCNKSKS---NSAADPDYC-RRILVRDAKGSIREIILPKGL------------ 95

  Fly   248 FPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKR-Q 311
             .|.:.::.|..||..|:|.||..|::.:|:...||..||..::|:.||||:||||.|.|.|: |
Human    96 -DLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQ 159

  Fly   312 AKEKAMAEQNQHNQPASSPRRV----------AVPVLVKDGKPCSGNNSSSQSQQHGTNSTSAGN 366
            .|:..:...........|..|:          .:|.|:   .||:.....|..:.....:..||.
Human   160 GKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALL---PPCATGALGSALRGPSLPALGAGA 221

  Fly   367 NTGSANNGNA----NSGIVSVTANVSGGL---------NLITGDAPNSHS----------PDTSS 408
            ..|||....|    .:|..|......||.         .|..|.....||          ...:|
Human   222 AAGSAAAAAAAAPGPAGAASPHPPAVGGAPGPGPAGPGGLHAGAPAAGHSLFSLPVPSLLGSVAS 286

  Fly   409 SLLASYGTVGGSNVAMLQQPCNNTLMSNSLAMAYRNQNN 447
            .|.::..|:.||....||: .:...:|:|....|...||
Human   287 RLSSAPLTMAGSLAGNLQE-LSARYLSSSAFEPYSRTNN 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	24/55 (44%)
VAX1	NP_001106175.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		COG5576	66..184	CDD:227863	38/131 (29%)
		Homeodomain	101..157	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..263		5/28 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	314..334		4/11 (36%)