Protein Alignment scro and LBX1

DIOPT Version :10

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_006553.2
• Gene: LBX1 / 10660
• HGNCID: 16960
• Length: 281
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 76/245 - (31%)
• Similarity: 100/245 - (40%)
• Gaps: 58/245 - (23%)

  Fly   109 NSNHS-TPFSVTDILSPIEESYRKLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMGTLY 172
            |||.. ||||:.|||              |.||..||.|..      |.......|:.:|.|
Human    28 NSNKPLTPFSIEDIL--------------NKPSVRRSYSLC------GAAHLLAAADKHAQG--- 69

  Fly   173 HSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASGTMSHMGNMSGLAA 237
                         .|.|||.....:.|          |..|:..|.|.:..|.     .:|.|.|
Human    70 -------------GLPLAGRALLSQTS----------PLCALEELASKTFKGL-----EVSVLQA 106

  Fly   238 CSVSDSKPL----QFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVK 298
            ....|...:    |.| .:|||.|..||..|:||||:||..|:|||..:|:.:|..:.||..||.
Human   107 AEGRDGMTIFGQRQTP-KKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVI 170

  Fly   299 IWFQNHRYKCKRQAKE-KAMAEQNQHNQPASSPRRVAVPVLVKDGKPCSG 347
            .||||.|.|.||..:| ||..|..:...|:.....||:..|.::.:..:|
Human   171 TWFQNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAG 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	28/55 (51%)
LBX1	NP_006553.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		3/6 (50%)
		Homeodomain	126..182	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..281		1/7 (14%)