Protein Alignment scro and nkx2-4

DIOPT Version :9

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: XP_002939478.1
• Gene: nkx2-4 / 100495653
• XenbaseID: XB-GENE-487481
• Length: 343
• Species: Xenopus tropicalis
• Alignment Length: 382
• Identity: 161/382 - (42%)
• Similarity: 205/382 - (53%)
• Gaps: 70/382 - (18%)

  Fly   112 HSTPFSVTDILSPIEESYRK---LELNGNPPSPF---------RSNSSSSSINSPGTLTTSTMAN 164
            |:||||||||||||||:|:|   :|..||..||.         ::.....|:....|:|| |...
 Frog     7 HTTPFSVTDILSPIEETYKKFGGMESTGNLSSPLGAYRQTHVSQTGMQQHSMGHNATVTT-TYHM 70

  Fly   165 PYAMGTLYHSPGVQTYC-GPTDNLSLAGHYTD-MRNSAS---WYGSTANDPRFA-ISRLMSSSAS 223
            |:::....|. .:..|| |...|:.....|.| |||||:   |||:. .|||:: |||.|..|..
 Frog    71 PHSVSQFSHG-AMGGYCNGGIGNMGDIPSYQDTMRNSAAATGWYGAN-TDPRYSTISRFMGPSTG 133

  Fly   224 GTMSHMGNMSGLAACSVSDSKPLQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLAS 288
            ..|:.||.:.|:|..:.| ..||.  .|.||||||||:||||||||||||||:||||||||||||
 Frog   134 MNMAGMGTLQGIAEAAKS-MAPLH--AAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLAS 195

  Fly   289 LIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQ--PASSPRRVAVPVLVKDGKPCSGNNSS 351
            :||||||||||||||||||.|||||:|...:..|.:.  ...|||||||||||||||||..::::
 Frog   196 MIHLTPTQVKIWFQNHRYKMKRQAKDKVTQQLQQESNLCQQQSPRRVAVPVLVKDGKPCQNSSNT 260

  Fly   352 SQSQQHGTNSTSAGNNTGSANNGNA-----NSGIVSVTANVSGGLNLITGDAPNSHSPDTSSSLL 411
            |...|..|...|..  ||..::.||     |..:        |.|:..:.....|.||.:..|.:
 Frog   261 STPNQQVTQQQSGA--TGGLSSSNAVHQHQNQQV--------GSLSQASELEEMSPSPQSLHSQV 315

  Fly   412 ASYGTVGGSNVAMLQQPCNNTLMSNSLAMAYRNQNNFISNGHQQQCGGYLPLQGRAW 468
            ||...:..|.|     ..:|.:::.|:                        |.||.|
 Frog   316 ASMAQIDTSAV-----DYSNGMVNPSM------------------------LYGRTW 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	49/52 (94%)
nkx2-4	XP_002939478.1	Homeobox	163..217	CDD:365835	49/53 (92%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	114	1.000	Domainoid score	I6014
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41526
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3379
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1348801at2759
OrthoFinder	1	1.000	-	-		FOG0002967
OrthoInspector	1	1.000	-	-		otm49066
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2571
SonicParanoid	1	1.000	-	-		X524
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090