Protein Alignment scro and nkx2-1

DIOPT Version :9

• Sequence 1: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: XP_002935383.1
• Gene: nkx2-1 / 100135015
• XenbaseID: XB-GENE-485985
• Length: 346
• Species: Xenopus tropicalis
• Alignment Length: 391
• Identity: 168/391 - (42%)
• Similarity: 202/391 - (51%)
• Gaps: 85/391 - (21%)

  Fly   112 HSTPFSVTDILSPIEESYRKLELN----GNPPSPF--RSNSSSSSINSPGTLTTSTMANPYAMGT 170
            |:|||||:|||||:||||:|:.:.    |.|.|..  :|..|.:|:...|      |.:...:..
 Frog     7 HTTPFSVSDILSPLEESYKKVAMESAGLGAPLSAAYRQSQVSQASMQQHG------MGHNGPVSA 65

  Fly   171 LYH--SPGVQT--------YC----GPTDNLSLAGHYTD-MRNSAS--WYGSTANDPRFA-ISRL 217
            .||  :.||..        ||    |...|:|....|.| ||||::  |||:.. ||||: |||.
 Frog    66 AYHMTAAGVPQLSHTTMGGYCNGNLGNLGNMSELPPYQDTMRNSSATGWYGANP-DPRFSTISRF 129

  Fly   218 MSSSASGTMSHMGNMSGLAACSVSDSKPLQFPLAQRRKRRVLFTQAQVYELERRFKQQRYLSAPE 282
            |..|:...|..:|||..|.....| ..|||  ...||||||||:||||||||||||||:||||||
 Frog   130 MGPSSGMNMGGLGNMGSLGDVGKS-MTPLQ--ATPRRKRRVLFSQAQVYELERRFKQQKYLSAPE 191

  Fly   283 REHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHN----QPASSPRRVAVPVLVKDGK 343
            ||||||:||||||||||||||||||.|||||:||..:|.|.:    |...|||||||||||||||
 Frog   192 REHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQMQQDNSSCQQQQSPRRVAVPVLVKDGK 256

  Fly   344 PC-SGNNS-----SSQSQQHGTNSTSAGNNTGSANNGNANSGIVSVTANVSGGLNLITGDAPNSH 402
            || :|:|:     .|..||..|..|...|..|...:...||      |..|..|      .|:|:
 Frog   257 PCQAGSNTPTAALQSHQQQTATAITVTSNGLGPHQSHQTNS------AGQSPDL------VPHSN 309

  Fly   403 SPDTSSSLLASYGTVGGSNVAMLQQPCNNTLMSNSLAMAYRNQNNFISNGHQQQCGGYLPLQGRA 467
            ||.:                  ||....:....||.:..|         |....|...  |.||.
 Frog   310 SPSS------------------LQNQVTSLSHLNSSSSDY---------GSAMSCSTL--LYGRT 345

  Fly   468 W 468
            |
 Frog   346 W 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	49/52 (94%)
nkx2-1	XP_002935383.1	Homeobox	165..219	CDD:365835	49/53 (92%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	114	1.000	Domainoid score	I6014
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3379
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002967
OrthoInspector	1	1.000	-	-		otm49066
Panther	1	1.100	-	-	O	PTHR24340
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2571
SonicParanoid	1	1.000	-	-		X524
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090