Protein Alignment AGO3 and AGO7

DIOPT Version :10

• Sequence 1: NP_001036627.2
• Gene: AGO3 / 3355150
• FlyBaseID: FBgn0250816
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: NP_177103.1
• Gene: AGO7 / 843276
• AraportID: AT1G69440
• Length: 990
• Species: Arabidopsis thaliana
• Alignment Length: 894
• Identity: 214/894 - (23%)
• Similarity: 362/894 - (40%)
• Gaps: 182/894 - (20%)

  Fly    82 HTSNQFITS-------ESKENITKKTK-----GPESEAIASENGLFF----PDLIYGSKGSSVNI 130
            |:..:|..|       |.|:...:|.|     ...|.:||.|.....    || ..|..||.:.:
plant   103 HSMTRFHKSLPVSQVVERKQQHQQKKKIQVSNNKVSGSIAIEEAALVVAKRPD-FGGQDGSVIYL 166

  Fly   131 YCNYLKLTTDESKGVFNYEVRFFP-PIDSVHLRIKYL---NDHKDKLGGTKTFDG-NTLYLPILL 190
            ..|:..:..|.|:.:::|.|...| |...:...||..   .|.....|....||| ..:|.|:..
plant   167 LANHFLVKFDSSQRIYHYNVEISPQPSKEIARMIKQKLVETDRNSFSGVVPAFDGRQNIYSPVEF 231

  Fly   191 PNKMTVFISKAEDVELQIRILY---KKKEEMRNCTQLYNILFDRVMKVLNYVKFDRKQ------- 245
            ......|.........:..:.|   ::|:..:...:|:.:    .||:::  |||.|:
plant   232 QGDRLEFFVNLPIPSCKAVMNYGDLREKQPQKKIEKLFRV----NMKLVS--KFDGKEQRKEGED 290

  Fly   246 FDPSRPKII----------PLAKL----------------EV------WPGYVTAVDEYKGGLML 278
            :.|..|:.|          |:.|.                |:      ..|:..::...:.||.|
plant   291 WAPLPPEYIHALDVILRENPMEKCTSIGRSFYSSSMGGSKEIGGGAVGLRGFFQSLRHTQQGLAL 355

  Fly   279 CCDVS----HRIL-----CQKTVLEMLVDL-----------YQQNVEHYQESARKMLVGNIVLTR 323
            ..|:|    |..:     .||. ||.|.||           .::.||...::.|..:.....:.|
plant   356 NMDLSITAFHESIGVIAYLQKR-LEFLTDLPRNKGRELSLEEKREVEKALKNIRVFVCHRETVQR 419

  Fly   324 YNNRTYKINDICFDQNPTCQFEIKTGCTSY---VEYYKQYHNINIKDVNQPLIYSIKKSRGIPAE 385
            |  |.|.:.:   :......|..:.|  .|   :.|:|.::...|:..|.|   .::.||..|
plant   420 Y--RVYGLTE---EITENIWFPDREG--KYLRLMSYFKDHYGYEIQFKNLP---CLQISRARP-- 472

  Fly   386 RENLQFCLIP-ELC-------YLTGLRDEVRSDNKLMREIATFTRVSPNQRQMALNKFYENVSNT 442
                  |.:| |||       :|..|.|:..:  |:|:    .....||:|:..::|.... |..
plant   473 ------CYLPMELCMICEGQKFLGKLSDDQAA--KIMK----MGCQKPNERKAIIDKVMTG-SVG 524

  Fly   443 PAAQEILNSWGLSLTNNSNKISGRQMDIEQIYFSKISVSAGRSAEFSKHAVTNEMLKVVHLSKWI 507
            |::......:.|.::.....:.||.:..     .|:.:...|:.:.||      :.|...:.:|.
plant   525 PSSGNQTREFNLEVSREMTLLKGRILQP-----PKLKLDRPRNLKESK------VFKGTRIERWA 578

  Fly   508 IIHL---RNYRQAATSLLDNMKQACESLGMNISNPTM-------------ISLDHDRIDAYIQAL 556
            ::.:   .:.:......::.:.|.||.||:.:|..|:             |||    :::.::.:
plant   579 LMSIGGSSDQKSTIPKFINELTQKCEHLGVFLSKNTLSSTFFEPSHILNNISL----LESKLKEI 639

  Fly   557 RRNITMNTQMVVCICHNRRDDRYAAIKKICCSEIPIPSQVINAKTLQNDLKIRS-VVQKIVLQMN 620
            :|..:.|.|:::|:. .::...|..:|:|..:.|.:.:|..   ...|..|:.| .|..:.|::|
plant   640 QRAASNNLQLIICVM-EKKHKGYGDLKRISETRIGVVTQCC---LYPNITKLSSQFVSNLALKIN 700

  Fly   621 CKLGGSLWTV--KIPF---------KNVMICGIDSYHDP--SNRGNSVAAFVASIN-SSYSQWYS 671
            .|:|||:..:  .||.         :.|:..|.|..|..  .:...||||.|.||| ...:::.|
plant   701 AKIGGSMTELYNSIPSHIPRLLRPDEPVIFMGADVTHPHPFDDCSPSVAAVVGSINWPEANRYVS 765

  Fly   672 KAVVQTKREEIVNGLSASFEIALKMYRKRNGKLPTNIIIYRDGIGDGQLYTCLNYEIPQFEMVCG 736
            :...||.|:||:..|....:..|..:.|...|||..||.:|||:.:.|....|..|:...:..|.
plant   766 RMRSQTHRQEIIQDLDLMVKELLDDFYKAVKKLPNRIIFFRDGVSETQFKKVLQEELQSIKTACS 830

  Fly   737 N----RIKISYIVVQKRINTRIFSGSGIHLENPLPGTVVDQHITKSNMYDFFLVSQLVRQGTVTP 797
            .    ...|::.|||||.:||:|.....| ||..||||||..||....:||:|.|.|..:||..|
plant   831 KFQDYNPSITFAVVQKRHHTRLFRCDPDH-ENIPPGTVVDTVITHPKEFDFYLCSHLGVKGTSRP 894

  Fly   798 THYVVLRDDCNYGPDIIQKLSYKLCFLYYNWAGTVRIPACCMYAHKLAY 846
            |||.:|.|:..:..|.:|:|.|.||:.:......:.|.....|||..||
plant   895 THYHILWDENEFTSDELQRLVYNLCYTFVRCTKPISIVPPAYYAHLAAY 943

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AGO3	NP_001036627.2	PAZ	291..425	CDD:198017	33/155 (21%)
		Piwi_piwi-like_Euk	412..850	CDD:240016	126/470 (27%)
AGO7	NP_177103.1	ArgoN	220..306	CDD:465134	17/91 (19%)
		ArgoL1	316..366	CDD:462567	7/49 (14%)
		PAZ	378..501	CDD:460472	32/142 (23%)
		Piwi_ago-like	532..949	CDD:240015	118/432 (27%)