Protein Alignment AGO3 and AGO10

DIOPT Version :10

• Sequence 1: NP_001036627.2
• Gene: AGO3 / 3355150
• FlyBaseID: FBgn0250816
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: NP_199194.1
• Gene: AGO10 / 834403
• AraportID: AT5G43810
• Length: 988
• Species: Arabidopsis thaliana
• Alignment Length: 845
• Identity: 201/845 - (23%)
• Similarity: 351/845 - (41%)
• Gaps: 138/845 - (16%)

  Fly   111 ENGLFFPDLIYGSKGSSVNIYCNYLKLTTDESKGVFNYEVRFFPPIDSVHLRIKYLND----HKD 171
            :|..|.|...:|:.|:...:..|:. |....:|.:..|:|...|.:.|..:....:.:    :|:
plant   124 KNSNFAPRPGFGTLGTKCIVKANHF-LADLPTKDLNQYDVTITPEVSSKSVNRAIIAELVRLYKE 187

  Fly   172 KLGGTK--TFDG-NTLYLPILLPNKMTVFISKAEDVE------------LQIRILYKKKEEMR-- 219
            ...|.:  .:|| .:||....||.....|..|..|.:            .::.|.:..:..|.
plant   188 SDLGRRLPAYDGRKSLYTAGELPFTWKEFSVKIVDEDDGIINGPKRERSYKVAIKFVARANMHHL 252

  Fly   220 ---------NCTQLYNILFDRVMKVLNYVKF---DRKQFDPSRPKIIPLAK-LEVWPGYVTAVDE 271
                     :|.|....:.|.|::.|:..:|   .|..|.|.......|.: ||.|.|:..::..
plant   253 GEFLAGKRADCPQEAVQILDIVLRELSVKRFCPVGRSFFSPDIKTPQRLGEGLESWCGFYQSIRP 317

  Fly   272 YKGGLMLCCDVSHRILCQK-TVLEMLVDLYQQNV------EHYQESARKMLVG-NIVLTRYNN-- 326
            .:.||.|..|::.....:. .|:|.:..|..::|      :..:...:|.|.| .:.:|...|
plant   318 TQMGLSLNIDMASAAFIEPLPVIEFVAQLLGKDVLSKPLSDSDRVKIKKGLRGVKVEVTHRANVR 382

  Fly   327 RTYKINDICFDQNPTCQFEIKTGCT--SYVEYYKQYHNINIKDVNQPLIY--SIKKSRGIPAERE 387
            |.|::..:.........|.:...||  |.:||:::.:...|:..:.|.:.  :.||:..:|.|.
plant   383 RKYRVAGLTTQPTRELMFPVDENCTMKSVIEYFQEMYGFTIQHTHLPCLQVGNQKKASYLPMEA- 446

  Fly   388 NLQFCLIPELCYLTGLRDEVRSDNKLMREIATFTRVSPNQRQMALNKFYENVSNT-----PAAQE 447
                |.|.|     |.|...|.:.|.:..:...|...|..|:   |.....|.:.     |.|:|
plant   447 ----CKIVE-----GQRYTKRLNEKQITALLKVTCQRPRDRE---NDILRTVQHNAYDQDPYAKE 499

  Fly   448 ILNSWGLSLTNNSNKISGRQMDIEQIYFSKISVSAGRSAEFSKHAVTN-EMLKVVHLSKWIIIHL 511
                :|::::.....:..|.:....:.:.:.........:..:..:.| :|:..:.:|:|..::.
plant   500 ----FGMNISEKLASVEARILPAPWLKYHENGKEKDCLPQVGQWNMMNKKMINGMTVSRWACVNF 560

  Fly   512 RNYRQ--AATSLLDNMKQACESLGMNISNPTMISLDHDRIDAYIQALRR--NITMN------TQM 566
            ....|  .|....:.:.|.||..||..:...:|.:...|.|...:||:.  :.:||      .::
plant   561 SRSVQENVARGFCNELGQMCEVSGMEFNPEPVIPIYSARPDQVEKALKHVYHTSMNKTKGKELEL 625

  Fly   567 VVCICHNRRDDRYAAIKKICCSEIPIPSQVINAKTLQNDLKI-RSVVQKIVLQMNCKLGG----- 625
            ::.|..:.....|..:|:||.:|:.:.||....|.:   .|| :..:..:.|::|.|:||
plant   626 LLAILPDNNGSLYGDLKRICETELGLISQCCLTKHV---FKISKQYLANVSLKINVKMGGRNTVL 687

  Fly   626 -SLWTVKIPFKN---VMICGIDSYHDPSN---RGNSVAAFVASINSSYSQW-----YSKAV-VQT 677
             ...:.:||..:   .:|.|.|..| |.|   ...|:||.|||     ..|     |:..| .|.
plant   688 VDAISCRIPLVSDIPTIIFGADVTH-PENGEESSPSIAAVVAS-----QDWPEVTKYAGLVCAQA 746

  Fly   678 KREEIVNGLSASFEIALK-------------MYRKRNGKLPTNIIIYRDGIGDGQLYTCLNYEIP 729
            .|:|::..|..:::..::             .:||..|:.|..||.||||:.:||.|..|.||:.
plant   747 HRQELIQDLYKTWQDPVRGTVSGGMIRDLLISFRKATGQKPLRIIFYRDGVSEGQFYQVLLYELD 811

  Fly   730 QFEMVCGN-----RIKISYIVVQKRINTRIFSGSGIHLE--------NPLPGTVVDQHITKSNMY 781
            .....|.:     :..:::||||||.:||:|:.:  |.:        |.|||||||..|.....:
plant   812 AIRKACASLEPNYQPPVTFIVVQKRHHTRLFANN--HRDKNSTDRSGNILPGTVVDTKICHPTEF 874

  Fly   782 DFFLVSQLVRQGTVTPTHYVVLRDDCNYGPDIIQKLSYKLCFLYYNWAGTVRIPACCMYAHKLAY 846
            ||:|.|....|||..|.||.||.|:.|:..|.||.|:..||:.|.....:|.|.....|||..|:
plant   875 DFYLCSHAGIQGTSRPAHYHVLWDENNFTADGIQSLTNNLCYTYARCTRSVSIVPPAYYAHLAAF 939

  Fly   847  846
            plant   940  939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AGO3	NP_001036627.2	PAZ	291..425	CDD:198017	31/146 (21%)
		Piwi_piwi-like_Euk	412..850	CDD:240016	129/496 (26%)
AGO10	NP_199194.1	PLN03202	131..988	CDD:215631	198/838 (24%)