Protein Alignment AGO3 and AGO5

DIOPT Version :10

• Sequence 1: NP_001036627.2
• Gene: AGO3 / 3355150
• FlyBaseID: FBgn0250816
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: NP_850110.1
• Gene: AGO5 / 817334
• AraportID: AT2G27880
• Length: 997
• Species: Arabidopsis thaliana
• Alignment Length: 1020
• Identity: 238/1020 - (23%)
• Similarity: 401/1020 - (39%)
• Gaps: 223/1020 - (21%)

  Fly     3 GRGNLLSLFNKNAGNMGKSISSKDHEIDSGLDFNNSESSGERLLSSHNIETDLITTLQHV--NIS 65
            |||..:|. .:..||:|:                 .|::|           ||..|...|  .:|
plant    44 GRGGSVSA-GRGRGNVGR-----------------GENTG-----------DLTATQVPVASAVS 79

  Fly    66 VGRGRARLID-TLKTDDHTSNQFITSESKE--------------NITKKTKGPESEAI--ASENG 113
            .||||..:.| |......:....:.|.|||              .||.....||..::  ||...
plant    80 GGRGRGNIGDPTFSVASSSKTVSVASSSKEESKNTEVSETMSNLQITSTETKPEMTSLPPASSKA 144

  Fly   114 LFFPDLI-YGSKGSSVNIYCNYLKLTTDESKGVFNYEVRFFPPIDS--VHLRIKYL--NDHKDK- 172
            :.||... .|:.|..|.:..|:. |.....:.:::|:|...|.:.|  |:..:..|  .::||.
plant   145 VTFPVRPGRGTLGKKVMVRANHF-LVQVADRDLYHYDVSINPEVISKTVNRNVMKLLVKNYKDSH 208

  Fly   173 LGG-TKTFDG-NTLYLPILLPNKMTVFI----------SKAEDVELQIRI-------LY------ 212
            ||| :..:|| .:||....||.....|:          |..:|...::.:       ||
plant   209 LGGKSPAYDGRKSLYTAGPLPFDSKEFVVNLAEKRADGSSGKDRPFKVAVKNVTSTDLYQLQQFL 273

  Fly   213 --KKKEEMRNCTQLYNILFDRVMKVLNYVKFDRKQFDPSRPKIIPLAK------------LEVWP 263
              |::|...:..|:.:::. |.....:||...|..|..|      |.|            :|.|.
plant   274 DRKQREAPYDTIQVLDVVL-RDKPSNDYVSVGRSFFHTS------LGKDARDGRGELGDGIEYWR 331

  Fly   264 GYVTAVDEYKGGLMLCCDVSHRILCQKTVLEMLV-------DLYQQNVEHYQESARKML-VGNIV 320
            ||..::...:.||.|..|||.|...:..|:...:       ||.:...:..:...:|:| ...:.
plant   332 GYFQSLRLTQMGLSLNIDVSARSFYEPIVVTDFISKFLNIRDLNRPLRDSDRLKVKKVLRTLKVK 396

  Fly   321 LTRYN-NRTYKINDICFDQNPTCQFEIKTGC-TSYVEYYKQYHNINIKDVNQPLIYSIKKSRGIP 383
            |..:| .::.||:.|........:|.::... .:.|:|:.:.:|..:|....|.|.:...:|.:
plant   397 LLHWNGTKSAKISGISSLPIRELRFTLEDKSEKTVVQYFAEKYNYRVKYQALPAIQTGSDTRPV- 460

  Fly   384 AERENLQFCLIP-ELCYL-TGLRDEVRSDNKLMREIATFTRVSPNQRQMAL-NKFYENVSNTPAA 445
                     .:| |||.: .|.|...|.:.|.:..:...|...|..|:.:: |...:|..|...:
plant   461 ---------YLPMELCQIDEGQRYTKRLNEKQVTALLKATCQRPPDRENSIKNLVVKNNYNDDLS 516

  Fly   446 QEILNSWGLSLTNNSNKISGRQMDIEQIYF---SKISVSAGRSAEFSKHAVTNEMLKVVHLSKWI 507
            :|    :|:|:|.....|..|.:....:.:   .|..:...|..::  :.:..:|:....::.|.
plant   517 KE----FGMSVTTQLASIEARVLPPPMLKYHDSGKEKMVNPRLGQW--NMIDKKMVNGAKVTSWT 575

  Fly   508 IIHL-----RNYRQAATSLLDNMKQACESLGMNIS-NPTM--ISLDHDRIDAYIQALRRNITMNT 564
            .:..     |...|.....|..|   |.|.||... .|.:  ||...:.|:..:..:.:. ....
plant   576 CVSFSTRIDRGLPQEFCKQLIGM---CVSKGMEFKPQPAIPFISCPPEHIEEALLDIHKR-APGL 636

  Fly   565 QMVVCICHNRRDDRYAAIKKICCSEIPIPSQVINAKTLQNDLKIRSVVQKIVLQMNCKLGGSLWT 629
            |:::.|..:.... |..||:||.:|:.|.||....:.: |.|. :..::.:.|::|.|.||....
plant   637 QLLIVILPDVTGS-YGKIKRICETELGIVSQCCQPRQV-NKLN-KQYMENVALKINVKTGGRNTV 698

  Fly   630 V------KIPF---KNVMICGIDSYHDPSNRGN--SVAAFVASIN-SSYSQWYSKAVVQTKREEI 682
            :      .||.   :..:|.|.|..|......:  |:||.|||:: ...:::......|..||||
plant   699 LNDAIRRNIPLITDRPTIIMGADVTHPQPGEDSSPSIAAVVASMDWPEINKYRGLVSAQAHREEI 763

  Fly   683 V----------------NGLSASFEIALKMYRKRNGKLPTNIIIYRDGIGDGQLYTCLNYEIPQF 731
            :                :||.....||   :|:..|::|..||.||||:.:||....|.:|:...
plant   764 IQDLYKLVQDPQRGLVHSGLIREHFIA---FRRATGQIPQRIIFYRDGVSEGQFSQVLLHEMTAI 825

  Fly   732 EMVCG----NRI-KISYIVVQKRINTRIF----------SGSGIHLENPLPGTVVDQHITKSNMY 781
            ...|.    |.: ::::::||||.:||:|          ..||    |..||||||..|...|.:
plant   826 RKACNSLQENYVPRVTFVIVQKRHHTRLFPEQHGNRDMTDKSG----NIQPGTVVDTKICHPNEF 886

  Fly   782 DFFLVSQLVRQGTVTPTHYVVLRDDCNYGPDIIQKLSYKLCFLYYNWAGTVRIPACCMYAHKLAY 846
            ||:|.|....|||..|.||.||.|:..:..|.:|.|:..||:.|.....:|.|.....|||..|:
plant   887 DFYLNSHAGIQGTSRPAHYHVLLDENGFTADQLQMLTNNLCYTYARCTKSVSIVPPAYYAHLAAF 951

  Fly   847 L-----------------------IGQSIQR--DVAEALSEKLFY 866
            .                       :||.|.:  .:.:.:.|.:||
plant   952 RARYYMESEMSDGGSSRSRSSTTGVGQVISQLPAIKDNVKEVMFY 996

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AGO3	NP_001036627.2	PAZ	291..425	CDD:198017	27/145 (19%)
		Piwi_piwi-like_Euk	412..850	CDD:240016	126/515 (24%)
AGO5	NP_850110.1	PLN03202	131..997	CDD:215631	212/904 (23%)