Protein Alignment AGO3 and piwil1

DIOPT Version :9

• Sequence 1: NP_001036627.2
• Gene: AGO3 / 3355150
• FlyBaseID: FBgn0250816
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: XP_002940227.2
• Gene: piwil1 / 100488735
• XenbaseID: XB-GENE-963233
• Length: 861
• Species: Xenopus tropicalis
• Alignment Length: 766
• Identity: 306/766 - (39%)
• Similarity: 468/766 - (61%)
• Gaps: 31/766 - (4%)

  Fly   122 GSKGSSVNIYCNYLKLTTDESKGVFNYEVRFFPPIDSVHLRIKYLNDHKDKLGGTKTFDGNTLYL 186
            ||.||.:.:..|::||.:.....:|.|.:.:.|.::|..||...|..|::.:|..:.|||..|:|
 Frog   107 GSSGSIIQLSTNHIKLISRPQWVLFQYHIDYAPQMESRGLRCALLFQHEELIGKARAFDGTMLFL 171

  Fly   187 PILLPNKMTVF--ISKAEDVELQIRILYKKKEEMRNCTQLYNILFDRVMKVLNYVKFDRKQFDPS 249
            |..|.....||  ....|.|::.|.:..:.......|.|.|||:|.|::|::|..:..|..::|:
 Frog   172 PKRLDKVNEVFSQTRNGETVKITITLTNELPPTSPTCFQFYNIIFRRLLKMMNMKQIGRNYYNPN 236

  Fly   250 RPKIIPLAKLEVWPGYVTAVDEYKGGLMLCCDVSHRILCQKTVLEMLVDLYQQNVEH-YQESARK 313
            ....|....|.::||:.|::.:|:..:||..||||::|..:|||:.:.::.|:...| :.:...|
 Frog   237 DQIEISSHGLTIYPGFSTSILQYENNIMLSIDVSHKVLRSETVLDYMYNVNQKVESHKFHDICSK 301

  Fly   314 MLVGNIVLTRYNNRTYKINDICFDQNPTCQFEIKTGC-TSYVEYYKQYHNINIKDVNQP-LIYSI 376
            .|:|.||||:|||:||:|:||.:|..|...|:...|. .|:|:||:..:|..|.|:||| |:::.
 Frog   302 DLIGQIVLTKYNNKTYRIDDINWDFTPESTFKKSDGSEISFVDYYRTQYNKGITDLNQPALVHNP 366

  Fly   377 KKSRG---IPAERENLQFCLIPELCYLTGLRDEVRSDNKLMREIATFTRVSPNQRQMALNKFYEN 438
            ||.||   :||.    ...||||.|:||||.|.:|||..:|:::|..||::|.||::.:.||.:|
 Frog   367 KKPRGPQNVPAG----PILLIPEFCFLTGLTDRMRSDFNVMKDLAIHTRLAPEQREIQVGKFLKN 427

  Fly   439 VSNTPAAQEILNSWGLSLTNNSNKISGRQMDIEQIYFSKISVSAGRSAEF-------SKHAVTNE 496
            :....:.|:.|..|||:..:.....:||....|:|      :.||::|::       |:......
 Frog   428 IHKDDSVQKELQDWGLNFDSKLLPFAGRVAPAEKI------LQAGKTADYNPQFADWSRELRGPT 486

  Fly   497 MLKVVHLSKWIIIHLRNYRQAATSLLDNMKQACESLGMNISNPTMISLDHDRIDAYIQALRRNIT 561
            :::|.||..|::::.|....||.:|..|:.:....:|:.::...|:.:| |..|||::.|::.:|
 Frog   487 LIRVKHLDNWVLLYTRRNYDAANTLTQNLFKVSGQMGIKMNRAVMVEVD-DTTDAYVKVLQQKVT 550

  Fly   562 MNTQMVVCICHNRRDDRYAAIKKICCSEIPIPSQVINAKTLQNDLKIRSVVQKIVLQMNCKLGGS 626
            .:.|||||:..:.|.|:|.||||..|.:.|:|||.:.||||.....:.||..||.||||||:||.
 Frog   551 PDVQMVVCLLSSNRKDKYDAIKKYLCIDCPVPSQCVLAKTLNKPQTVVSVATKIALQMNCKMGGE 615

  Fly   627 LWTVKIPFKNVMICGIDSYHDPSNRGNSVAAFVASINSSYSQWYSKAVVQTKREEIVNGLSASFE 691
            ||||:||.|.:||.|||.|||..:...|:.|||||:|.|.::|:|:.|:|.:::|||:||.....
 Frog   616 LWTVEIPLKELMIVGIDCYHDTLSGKRSIGAFVASLNPSMTRWFSRCVLQAQKQEIVDGLKVCMH 680

  Fly   692 IALKMYRKRNGKLPTNIIIYRDGIGDGQLYTCLNYEIPQFEMVCGN-----RIKISYIVVQKRIN 751
            .|||.:...|..||:.|||||||:|||||.|.:.|||||.:....:     ..|::.|||:||::
 Frog   681 AALKAWFNCNKSLPSRIIIYRDGVGDGQLKTMVEYEIPQLQDCIRSAEKDYSPKLTVIVVKKRVS 745

  Fly   752 TRIFSGSGIHLENPLPGTVVDQHITKSNMYDFFLVSQLVRQGTVTPTHYVVLRDDCNYGPDIIQK 816
            .|.|:..|..|:||.|||:||..||:...||||::||.||.|:|:||||.|:.|.....||.:|:
 Frog   746 ARFFAHVGGRLQNPPPGTIVDVEITRPEWYDFFIISQSVRVGSVSPTHYNVVYDSGALKPDHMQR 810

  Fly   817 LSYKLCFLYYNWAGTVRIPACCMYAHKLAYLIGQSIQRDVAEALSEKLFYL 867
            |:||||.|||||.|.:|:||.|.||||||:|:||||.|:....||::|:||
 Frog   811 LTYKLCHLYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPHLTLSDRLYYL 861

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AGO3	NP_001036627.2	PAZ	291..425	CDD:198017	58/139 (42%)
		Piwi_piwi-like_Euk	412..850	CDD:240016	190/449 (42%)
piwil1	XP_002940227.2	GAGE	16..107	CDD:368631	306/766 (40%)
		ArgoL1	227..273	CDD:370073	14/45 (31%)
		PAZ_piwi_like	276..393	CDD:239211	49/120 (41%)
		Piwi_piwi-like_Euk	401..844	CDD:240016	190/449 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54391
OrthoDB	1	1.010	-	-		D220258at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020