Protein Alignment p120ctn and Pkp1

DIOPT Version :10

• Sequence 1: NP_001036444.1
• Gene: p120ctn / 3355143
• FlyBaseID: FBgn0260799
• Length: 781
• Species: Drosophila melanogaster
• Sequence 2: NP_001381145.1
• Gene: Pkp1 / 304822
• RGDID: 1307472
• Length: 728
• Species: Rattus norvegicus
• Alignment Length: 694
• Identity: 187/694 - (26%)
• Similarity: 306/694 - (44%)
• Gaps: 108/694 - (15%)

  Fly    25 SLTHEPANMQ-SQFGSFQNYDQFSAAGYSSTPLYITKPTGVGAITKVAPHCSQNKIETNSTDNSI 88
            :|..||.|.: |.:...:|:.:....|..:|       ||.|     :..|...||:.:.::
  Rat   108 TLKREPDNRRFSSYSQMENWSRHYPRGSCAT-------TGAG-----SDICFMQKIKASRSE--- 157

  Fly    89 PDIENHPLATTVRYVQAGQYEDTSE--YGVAGLTCGIDSEYTAEAVVPYCYTSDANYTGIQNTTS 151
            ||:...|..|..:....|:.:.|::  |.... ||      :.:..|..|.....:.|..|:..
  Rat   158 PDLYCDPRGTLRKGTLGGKGQKTTQNRYSFYS-TC------SGQKAVKKCPVRPPSCTSKQDPV- 214

  Fly   152 SIKPFSGRPFNDNINGAEAVADSQ-CRTFKSSAEFKLPQFAMSSINTVPQRLEEKDDYIEGSEND 215
            .:.|.|   .|.:::...:.|.|: |                                   ||:.
  Rat   215 CMPPIS---CNKDMSFGHSRASSKIC-----------------------------------SEDI 241

  Fly   216 ICSTMRWRDPNLSEVISFLSNPSSAIKANAAAYLQHLCYMDDPNKQRTRSLGGIPPLVRLLSYDS 280
            .||.:     .:.:.:.:|.:.....:|..|.|:||.|:.|:..||:...||||..||.||...:
  Rat   242 ECSGL-----TIPKAVQYLCSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN 301

  Fly   281 PEIHKNACGALRNLSYGRQNDENKRGIKNAGGIAALVHLLCRSQETEVKELVTGVLWNMSSCEDL 345
            ..:.:.|.||||||.:  ::..||...:...||...|.||.||..||:::.:||:|||:||.::|
  Rat   302 QNVQQAAAGALRNLVF--RSTTNKLETRRQNGIREAVSLLRRSGSTEIQKQLTGLLWNLSSTDEL 364

  Fly   346 KRSIIDEALVAVVCSVIKPHSGWDAVCCGETCFS------TVFRNASGVLRNVSSAGEHARGCLR 404
            |..::.:||..:...||.|.|||   |.|.:..|      .||.||:|.|||:||| :..|..:|
  Rat   365 KEELVADALPVLTDRVIIPFSGW---CDGNSNMSREVVDPEVFFNATGCLRNLSSA-DAGRQTMR 425

  Fly   405 NCEHLVECLLYVVRTSIEKNNIGNKTVENCVCILRNLSYRCQEVDDPNYDKHPFITPERVIPSSS 469
            |...|::.|:..|:..:..:...:|:||||:|||.|||||........|.:..:.|.......||
  Rat   426 NYSGLIDSLMAYVQNCVAASRCDDKSVENCMCILHNLSYRLDAEVPTRYRQLEYNTRNAYTEKSS 490

  Fly   470 KGENLGCFGTNKKKKEANNSDA-LNEYNISADYSKSSVTYNKLNKGYEQLWQPEVVQYYLSLLQS 533
                .|||.....|...||.|. |.|...:.             ||...|:..:.::.||:|:..
  Rat   491 ----TGCFSNRGDKMMNNNYDCPLPEEETNP-------------KGSSWLYHSDAIRTYLNLMGK 538

  Fly   534 CSNPETLEAAAGAIQNLSACYWQPSIDIRATVR-KEKGLPILVELLRMEVDRVVCAVATALRNLA 597
            .....||||.|||:|||:|.....|..:...:. ||||||.:..||:.....||.:.|:.|.|::
  Rat   539 SKKDATLEACAGALQNLTASKGLMSNGMSQLIGIKEKGLPQIARLLQSGNSDVVRSGASLLSNMS 603

  Fly   598 IDQRNKELIGKYAMRDLVQKLPSGNVQHDQNT--SDDTITAVLATINEVIKKNPEFSRSLLDSGG 660
            .......::|.....::.:.|.|    |..||  |:|.:::...|:..::...|:.::....:..
  Rat   604 RHPVLHRVMGNQVFPEVTRLLTS----HTGNTSNSEDILSSACYTVRNLMTSQPQMAKQYFSNSM 664

  Fly   661 IDRLMNITKRKEKYTSCVLKFASQVLYTMWQHNELRDVYKKNGW 704
            ::.:.|:. |....:....:.|..:|..||...||:.|.::.|:
  Rat   665 LNNVFNLC-RNSASSPKAAEAARLLLSDMWASKELQSVLRQQGF 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p120ctn	NP_001036444.1	armadillo repeat	227..252	CDD:293788	5/24 (21%)
		Arm	256..295	CDD:425727	17/38 (45%)
		armadillo repeat	260..296	CDD:293788	17/35 (49%)
		ARM	300..341	CDD:214547	16/40 (40%)
		armadillo repeat	304..339	CDD:293788	14/34 (41%)
		armadillo repeat	347..392	CDD:293788	18/50 (36%)
		armadillo repeat	515..556	CDD:293788	15/40 (38%)
		Arm	516..552	CDD:425727	14/35 (40%)
		ARM	560..597	CDD:214547	13/37 (35%)
		armadillo repeat	562..596	CDD:293788	12/34 (35%)
		armadillo repeat	601..641	CDD:293788	8/41 (20%)
Pkp1	NP_001381145.1	armadillo repeat	240..273	CDD:293788	7/37 (19%)
		ARM	277..317	CDD:214547	18/39 (46%)
		armadillo repeat	281..317	CDD:293788	17/35 (49%)
		ARM	319..360	CDD:214547	16/40 (40%)
		armadillo repeat	323..358	CDD:293788	14/34 (41%)
		armadillo repeat	365..416	CDD:293788	20/53 (38%)
		Arm	516..557	CDD:425727	16/53 (30%)
		armadillo repeat	569..604	CDD:293788	13/34 (38%)
		ARM	572..604	CDD:214547	13/31 (42%)
		armadillo repeat	610..648	CDD:293788	9/41 (22%)