| Sequence 1: | NP_001036444.1 | Gene: | p120ctn / 3355143 | FlyBaseID: | FBgn0260799 | Length: | 781 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001091679.1 | Gene: | CTNNB1 / 1499 | HGNCID: | 2514 | Length: | 781 | Species: | Homo sapiens |
| Alignment Length: | 837 | Identity: | 169/837 - (20%) |
|---|---|---|---|
| Similarity: | 288/837 - (34%) | Gaps: | 259/837 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 22 MDLSLTHEPANMQSQFGSFQNYDQFSAAGYSSTPLYITKPTGVGAITKVAPHCS------QNKIE 80
Fly 81 TNS-------------TDNSIPDIENHPLATTVRYVQAGQYEDTSEYGVAGLTCGIDSEYTAEA- 131
Fly 132 -------VVPYCYTSDANYTGIQNTTSSIKPFSGRPFNDN----INGAEAVADSQCRTFKSS--A 183
Fly 184 EFKLPQFAMSSINTVPQRLEEKDDYIEGSENDICSTMR-------------------WRDPNLSE 229
Fly 230 VISFLSNPSSAIKANAAAYLQHLCYMDDPNKQRTRSLGGIPPLVRLLSYDSPEIHKNACGALRNL 294
Fly 295 SYGRQNDENKRGIKNAGGIAALVHLLCRSQETEVKELVTGVLWNMSSCEDLKRSIIDEALVAVVC 359
Fly 360 SVIKP----HSGWDAVCCGETCFS-TVFRNASGVLRNVSSAG---EHARGCLRNCEHL------- 409
Fly 410 -VECLLYVVRTSIEKNNIGNKTV------------------------ENCVCILRNLSYRCQEVD 449
Fly 450 DPNYDKHPFITPERVIPSSSKGENLGCFGTNKKKKEANNSDALNEYNISADYSKSSVTYNKLNKG 514
Fly 515 YEQLWQPEVVQYYLSLLQSCSNPETLEAAAGAIQNLSACYWQPSIDIRATVRKEKGLPILVELL- 578
Fly 579 -----------------------RMEVDRVVCAVATALRNLAIDQRNKELI-GKYAMRDLVQKL- 618
Fly 619 -PSGNVQHDQNTSDDTITAVLATINEVIKKNPEFSRSLLDSGGIDRLMNITKRKEKYTSCVLKFA 682
Fly 683 SQVLYTMWQHNELRDVYKKNGWKEQDFVSKHFTAHNTPPSSPNNVNNTLNRPMASQG 739 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| p120ctn | NP_001036444.1 | ARM | 227..341 | CDD:237987 | 29/113 (26%) |
| armadillo repeat | 227..252 | CDD:293788 | 4/24 (17%) | ||
| armadillo repeat | 260..296 | CDD:293788 | 9/35 (26%) | ||
| armadillo repeat | 304..339 | CDD:293788 | 11/34 (32%) | ||
| ARM | 307..442 | CDD:237987 | 43/174 (25%) | ||
| armadillo repeat | 347..392 | CDD:293788 | 13/49 (27%) | ||
| armadillo repeat | 515..556 | CDD:293788 | 12/40 (30%) | ||
| ARM | 516..643 | CDD:237987 | 40/153 (26%) | ||
| armadillo repeat | 562..596 | CDD:293788 | 13/57 (23%) | ||
| armadillo repeat | 601..641 | CDD:293788 | 11/42 (26%) | ||
| CTNNB1 | NP_001091679.1 | Interaction with VCL. /evidence=ECO:0000250 | 2..23 | 6/27 (22%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 34..57 | 6/23 (26%) | |||
| SRP1 | 142..>431 | CDD:227396 | 72/322 (22%) | ||
| ARM 1 | 151..191 | 10/40 (25%) | |||
| armadillo repeat | 153..178 | CDD:293788 | 7/25 (28%) | ||
| Interaction with BCL9. /evidence=ECO:0000269|PubMed:17052462 | 156..178 | 6/22 (27%) | |||
| armadillo repeat | 188..221 | CDD:293788 | 7/45 (16%) | ||
| ARM 2 | 193..234 | 6/53 (11%) | |||
| armadillo repeat | 230..262 | CDD:293788 | 4/31 (13%) | ||
| ARM | 230..262 | CDD:214547 | 4/31 (13%) | ||
| ARM 3 | 235..276 | 7/40 (18%) | |||
| armadillo repeat | 270..306 | CDD:293788 | 9/35 (26%) | ||
| ARM 4 | 277..318 | 13/42 (31%) | |||
| armadillo repeat | 312..347 | CDD:293788 | 14/51 (27%) | ||
| ARM 5 | 319..360 | 18/57 (32%) | |||
| ARM | 350..390 | CDD:214547 | 12/39 (31%) | ||
| armadillo repeat | 354..389 | CDD:293788 | 10/34 (29%) | ||
| ARM 6 | 361..389 | 8/27 (30%) | |||
| ARM 7 | 400..441 | 9/41 (22%) | |||
| armadillo repeat | 402..427 | CDD:293788 | 4/25 (16%) | ||
| Arm | 431..473 | CDD:395413 | 8/41 (20%) | ||
| armadillo repeat | 435..473 | CDD:293788 | 6/37 (16%) | ||
| ARM 8 | 442..484 | 9/92 (10%) | |||
| armadillo repeat | 482..517 | CDD:293788 | 12/46 (26%) | ||
| ARM 9 | 489..530 | 16/54 (30%) | |||
| armadillo repeat | 524..582 | CDD:293788 | 14/59 (24%) | ||
| ARM 10 | 531..571 | 8/41 (20%) | |||
| Arm | 583..622 | CDD:395413 | 12/49 (24%) | ||
| armadillo repeat | 587..621 | CDD:293788 | 10/44 (23%) | ||
| ARM 11 | 594..636 | 9/52 (17%) | |||
| armadillo repeat | 629..662 | CDD:293788 | 6/35 (17%) | ||
| ARM 12 | 637..666 | 6/38 (16%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 705..781 | 169/837 (20%) | |||
| Interaction with SCRIB. /evidence=ECO:0000250 | 772..781 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2332 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.940 | |||||