Protein Alignment CG17883 and GYP8

DIOPT Version :9

• Sequence 1: NP_001036448.1
• Gene: CG17883 / 3355139
• FlyBaseID: FBgn0040005
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_444296.1
• Gene: GYP8 / 850517
• SGDID: S000001867
• Length: 497
• Species: Saccharomyces cerevisiae
• Alignment Length: 430
• Identity: 94/430 - (21%)
• Similarity: 172/430 - (40%)
• Gaps: 87/430 - (20%)

  Fly    10 NFEKCPESDDELKKRLEIEKLINKNIDKNISFDVLVKLSLAPYGLVNDDFRRILWPQLAGVDINH 74
            :..:|.....|.:|...|.||:.|...:.:.:     :.|.|.|.||:..|:..|.:|....:..
Yeast    30 SLSRCDSGKAEEQKGKVISKLLEKKDVRALRY-----IGLGPLGFVNNSLRKDCWYELLASQLLI 89

  Fly    75 LGQAPTLDKFQCHPEYNQVVLDVNRSLKRFPPGIPYEQRIALQDQLTVLILRVIQKYPNLRYYQG 139
            ......:...:.|.:..||:||..||   |...:....::.|:..|..||.||::|||.|.||||
Yeast    90 DDATEYITPVEKHKDEGQVILDAERS---FGGIVDKNLKLQLRKLLVELITRVLRKYPTLNYYQG 151

  Fly   140 YHDVAVTFL-----------------LVVGEEI----AFAIMEQLSTTHFSECMQETMEATQRRL 183
            |||:...|:                 |.:.|||    .|..:|..:..:..:.|..:::.:..:|
Yeast   152 YHDIVSVFIMCFSWNVTKENGLELENLSLQEEIDMERLFYCIEAFTLLYLRDFMMNSLDFSFEQL 216

  Fly   184 MFIWPIIKFENPELYQFLQNSTVGTLFSLPWYLTWFGHSL--------TSYRTVVRLYDYFLA-S 239
            ..|..:||..|.:.|...:......||::...||.|.|:|        ..::.:.:::|..:: .
Yeast   217 RVISSLIKESNMKFYNLFKFDENEPLFAIGSILTIFAHNLKPIDSGDNNLHKILFQIFDMTISMQ 281

  Fly   240 PIYTSIFVTAAILLYRSDEILKE----------DCDM---ASVHCLLSVIPEDLPFEDLLK---- 287
            .:...:.:...:||..:.||.|:          |.|:   |....|...:.::..:|::|:
Yeast   282 SMRLPLIIYKNLLLQNASEISKQIEANSDFFENDFDLRHGAIQTVLQKKLYDEALWEEVLQITRK 346

  Fly   288 --TSSS-------LLNKYSL---------------TLIEKDVEELICQERRKRKTDEALIVKRRQ 328
              |::|       .|||||.               |:|....|:....|..|.:....:..:.:.
Yeast   347 DATTASKKALKRVSLNKYSALLNTACGKPGCFDMSTIIFYLSEQTKMNEHYKEEKYHGVAARSKT 411

  Fly   329 PATSNRIPIITKWLPNILTAKPVILTTAISIVVGVCAYYY 368
            .|...|   :..:||:....     .:.||:::|:.|..|
Yeast   412 RALVQR---LGHFLPSKYNR-----WSKISLLIGIVAILY 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17883	NP_001036448.1	RabGAP-TBC	91..260	CDD:278964	49/198 (25%)
GYP8	NP_444296.1	COG5210	2..497	CDD:227535	94/430 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346571
Domainoid	1	1.000	64	1.000	Domainoid score	I2456
eggNOG	1	0.900	-	-		E1_KOG2595
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	81	1.000	Inparanoid score	I1618
Isobase	1	0.950	-	0	Normalized mean entropy	S3290
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003660
OrthoInspector	1	1.000	-	-		oto100206
orthoMCL	1	0.900	-	-		OOG6_103152
Panther	1	1.100	-	-	LDO	PTHR20913
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R538
SonicParanoid	1	1.000	-	-		X2532
TreeFam	0	0.000	Not matched by this tool.
	13	12.770