DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17883 and gyp10

DIOPT Version :9

Sequence 1:	NP_001036448.1	Gene:	CG17883 / 3355139	FlyBaseID:	FBgn0040005	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_595501.1	Gene:	gyp10 / 2541149	PomBaseID:	SPBC651.03c	Length:	373	Species:	Schizosaccharomyces pombe

Alignment Length:	305	Identity:	85/305 - (27%)
Similarity:	143/305 - (46%)	Gaps:	42/305 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 KRLEIEKLINKNIDK----NISFDVLVKLSLAPYGLVNDDFRRILWPQLAGVDINHLGQAPTLDK 83
            |:.||::|  ||..|    |...:.|..:....:|.:....|:.:|..|.|:...|        :
pombe     2 KKKEIKQL--KNEIKIALLNSDVETLSHIGKEGHGFLMKSLRKSVWVSLCGLSCRH--------R 56

  Fly    84 FQC---------HPEYNQVVLDVNRSLKRFP--PGIPYEQRIALQDQLTVLILRVIQKYPNLRYY 137
            .:|         :.:.|||.||..||..::.  |.:..:.|    .|||.|:..|.:.||.|.||
pombe    57 MECLSRSTSQSSYADQNQVHLDSERSFFQYKLNPFLLRKHR----SQLTKLLSVVFKHYPELCYY 117

  Fly   138 QGYHDVAVTFLLVVGEEIAFAIMEQLSTTHFSECMQETMEATQRRLMFIWPIIKFENPELYQFLQ 202
            ||.||:|...||.:....|..:||.|......:.|..|::.|.::|..|..:||..:|.||::|.
pombe   118 QGLHDIAQILLLTLPFSHALPLMEHLVFYRLRDFMLPTLDGTVKQLQLILAVIKARDPTLYEYLI 182

  Fly   203 NSTVGTLFSLPWYLTWFGHSLTSYRTVVRLYDYFLASPIYTSIFVTAAILLYRSD---EILKEDC 264
            .:.:...|:|.|.:|||.|.::....|.||:|:|::|...|.::..|.::|....   |:|.::.
pombe   183 KADIQCYFALSWLITWFAHDVSDISVVCRLFDFFISSHPLTVVYTCAQVVLDNRTSIIELLWDNS 247

  Fly   265 DMASVHCLLSVIPEDLPFEDLLKTS---------SSL-LNKYSLT 299
            ....:|..|..:|..:....|:|.:         ||| |::|.::
pombe   248 GADLLHSYLCKLPASINVNQLIKNTCATISAVPFSSLPLDRYQIS 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17883	NP_001036448.1	RabGAP-TBC	91..260	CDD:278964	58/173 (34%)
gyp10	NP_595501.1	COG5210	1..373	CDD:227535	85/305 (28%)
gyp10	NP_595501.1	RabGAP-TBC	72..240	CDD:278964	57/171 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	109	1.000	Domainoid score	I1633
eggNOG	1	0.900	-	-		E1_KOG2595
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32574
Inparanoid	1	1.050	120	1.000	Inparanoid score	I1500
OMA	1	1.010	-	-		QHG54480
OrthoFinder	1	1.000	-	-		FOG0003660
OrthoInspector	1	1.000	-	-		oto101963
orthoMCL	1	0.900	-	-		OOG6_103152
Panther	1	1.100	-	-	LDO	PTHR20913
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R538
SonicParanoid	1	1.000	-	-		X2532
TreeFam	1	0.960	-	-
	14	13.860