Protein Alignment CG17883 and tbc-20

DIOPT Version :9

• Sequence 1: NP_001036448.1
• Gene: CG17883 / 3355139
• FlyBaseID: FBgn0040005
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_497068.2
• Gene: tbc-20 / 175139
• WormBaseID: WBGene00013196
• Length: 411
• Species: Caenorhabditis elegans
• Alignment Length: 349
• Identity: 112/349 - (32%)
• Similarity: 181/349 - (51%)
• Gaps: 49/349 - (14%)

  Fly    23 KRLEIEKLINKNIDKNIS--FDVLVKLSLAPYGLVNDDFRRILWPQLA-----GVDINHLG---- 76
            ||..|::.:.|:..:::|  .|.|...:::|.|||:|:||.::||.|:     ..|::.:.
 Worm    49 KREAIDRFLKKHRKEDLSLYIDELRDFAISPGGLVDDEFRAVIWPVLSANLVQNDDLDDVSSSYD 113

  Fly    77 -----------QAP--------TLDKFQCHPEYNQVVLDVNRSLKRFPPGIPYEQRIALQDQLTV 122
                       :.|        ||:..:.|.|:|||.|||:|:|.||||.|....|..||.:|..
 Worm   114 SDFESAQSDFDEEPAYEESEELTLEDLKGHKEWNQVELDVHRTLSRFPPNISDTHRDVLQTELIP 178

  Fly   123 LILRVIQKYPNLRYYQGYHDVAVTFLLVVGEEIAFAIMEQLSTT-HFSECMQETME-ATQRRLMF 185
            ||:||:...|...||||:||:.:|.|||.||..|..:...|:.. .|:..:.:|:| :..|.|..
 Worm   179 LIVRVLSINPRFNYYQGFHDICLTVLLVCGEVDALPVCSNLAKNGSFNNYLLKTLEKSVVRELDL 243

  Fly   186 IWPIIKFENPELYQFLQNSTVGTLFSLPWYLTWFGHSLTSYRTVVRLYDYFLASPIYTSIFVTAA 250
            ::.|:...:|.|.|.:::..:||:|.|.|.||||.|:|..|:.:||.:|.||||.....|:|:||
 Worm   244 LYVILSRVDPSLEQVMRSVELGTMFGLSWPLTWFSHTLKQYQQIVRFFDVFLASSPLLPIYVSAA 308

  Fly   251 ILLYRSDEILKEDCDMASVHCLLSVIPEDLPFEDLLKTS---SSLLNKYSLTLIEKDVEELICQE 312
            ::::|...||..:.:|..:|.||:.:|.:||.:.::|.|   |.|:..              |..
 Worm   309 VVVFRRASILACEREMPFLHRLLTEMPHELPIDTIIKDSVYLSKLMPP--------------CLL 359

  Fly   313 RRKRKTDEALIVKRRQPATSNRIP 336
            :.|...:...||.:...|....||
 Worm   360 KTKYTNEYRKIVSKPSKAAVKTIP 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17883	NP_001036448.1	RabGAP-TBC	91..260	CDD:278964	69/170 (41%)
tbc-20	NP_497068.2	RabGAP-TBC	147..318	CDD:382990	69/170 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167393
Domainoid	1	1.000	140	1.000	Domainoid score	I2963
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32574
Inparanoid	1	1.050	174	1.000	Inparanoid score	I2716
Isobase	1	0.950	-	0	Normalized mean entropy	S3290
OMA	1	1.010	-	-		QHG54480
OrthoDB	1	1.010	-	-		D1107565at2759
OrthoFinder	1	1.000	-	-		FOG0003660
OrthoInspector	1	1.000	-	-		oto17853
orthoMCL	1	0.900	-	-		OOG6_103152
Panther	1	1.100	-	-	LDO	PTHR20913
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R538
SonicParanoid	1	1.000	-	-		X2532
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.850