Protein Alignment CG17486 and YML096W

DIOPT Version :9

• Sequence 1: NP_001036446.2
• Gene: CG17486 / 3355138
• FlyBaseID: FBgn0032997
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_013613.1
• Gene: YML096W / 854877
• SGDID: S000004562
• Length: 525
• Species: Saccharomyces cerevisiae
• Alignment Length: 625
• Identity: 173/625 - (27%)
• Similarity: 264/625 - (42%)
• Gaps: 168/625 - (26%)

  Fly     1 MCGI---FCSVVNNVPLNS----------------FNISSAL-KVI--LKNRGPDVQDEVVIDYC 43
            ||||   :|.  ||..||.                .|.||.. |:|  :..|||        :|.
Yeast     1 MCGILLHYCP--NNNYLNDELIEFPEGTEFGDTTCTNESSIFNKIIPYIAARGP--------NYS 55

  Fly    44 FGKILFAGFVLWQQGESVQKQPV------VEDDFIFLFNGDIYNTSKPEYMSDTTWIAERLAECR 102
            ..:.:.|..:.|.......:||.      |:|.:...|||::||....:..:|:.:||..|...:
Yeast    56 SLRAVKAYRISWFSSVLSLRQPFTKQSINVDDRYFLQFNGELYNKEISQGDNDSLYIASMLQNLK 120

  Fly   103 CKEQNILKILKRLEGPHCLIIYDKREQILYFSRDALGRNSLLIERICNGFQLLSTSHFEDKK--I 165
             :...::.::|.|||.:...|||.....|||.||.:||.|            ||.|...|.:  :
Yeast   121 -EGMGVIDVIKSLEGEYAYTIYDVNSSKLYFGRDPIGRRS------------LSYSVTPDNELYV 172

  Fly   166 SLELPPLGLFRVKLNDLNSCVLYPWQPLNNYSTQLLRNLDLAIGWKTAVESPMSPDWMLNCNPAF 230
            :......|.|:    |....|:|      .|.|:..                     :||.|..
Yeast   173 ASVTGSAGSFQ----DCIGGVIY------EYDTRTK---------------------LLNSNQR- 205

  Fly   231 SYNFYEFQYIKNNVNLYKNLIDQSEIKYTLSILHTLLSDSIKNRVRNMAPFCRLCMQKLNISPPC 295
            |:..||   :.:.::|  |....||:...   |:.:|.||:|.||.::.|
Yeast   206 SHLPYE---VTSEIDL--NFTSLSEVSKN---LYAVLRDSVKKRVESIHP--------------- 247

  Fly   296 RH---AKLCILFSGGLDCTILALLANQFVPVNE------PIELINVAFESVKGQNISEKLF--DV 349
            ||   :.:.:|||||:||:::..|..:.:..|:      .|||:||:||     |....||  |.
Yeast   248 RHIENSPIAVLFSGGIDCSVIVALICEVLQENDYKCGKPVIELLNVSFE-----NPRTGLFPSDT 307

  Fly   350 PDRKTSLVSVNELKQLCPERCWNLLKVNVTRLELQQHLTSR--IKHLIYPLDTVLDESLGCAFWF 412
            ||||.|:.|...|:.|.|.....|::|:|   ...::|..:  :.:|:||..|.:|.|:..||:|
Yeast   308 PDRKLSINSAKTLQNLYPNVDIKLVEVDV---PYDEYLKWKPFVINLMYPKQTEMDLSIAIAFFF 369

  Fly   413 AS---------------HCTHSTARVALIGSGADELFGGYTRYRNSYSRCLGNDLERQLAVQNEL 462
            ||               :..|..  |...|.|||||:|||.::.|.....|..:|.||:
Yeast   370 ASRGRGFLTSLNGERTPYQRHGI--VLFSGLGADELYGGYHKFANKPPHELVEELTRQI------ 426

  Fly   463 ERDWQRISARNLARDDRIIADTGKTARSPFIEENFVKF-IRSLEVYQKCCFGFPEGVGDKLLLRL 526
                ..|..|||.|||::||..|...|.||::|..:|. ...:.:..|.         :||:||.
Yeast   427 ----NNIYDRNLNRDDKVIAHNGVEVRYPFLDEYVIKLSTAEIPINFKV---------NKLILRK 478

  Fly   527 YGYQ-IGLRDVVFLKKRAIQFGSRIANKKQNGS-HQSDNL 564
            ...| :.|..:....|||||||::.|...::|: |.:|.|
Yeast   479 VASQYLKLDGISSEPKRAIQFGAKSAKMTKDGNKHGTDLL 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17486	NP_001036446.2	Gn_AT_II_novel	1..175	CDD:239735	53/203 (26%)
		Asn_Synthase_B_C	266..547	CDD:238949	96/310 (31%)
YML096W	NP_013613.1	AsnB	1..513	CDD:223444	170/618 (28%)
		Gn_AT_II_novel	1..191	CDD:239735	56/216 (26%)
		Asn_Synthase_B_C	232..500	CDD:238949	96/311 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344102
Domainoid	1	1.000	71	1.000	Domainoid score	I2256
eggNOG	1	0.900	-	-		E1_COG0367
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6564
Inparanoid	1	1.050	137	1.000	Inparanoid score	I1199
Isobase	1	0.950	-	0	Normalized mean entropy	S3476
OMA	1	1.010	-	-		QHG55715
OrthoFinder	1	1.000	-	-		FOG0004855
OrthoInspector	1	1.000	-	-		oto99982
orthoMCL	1	0.900	-	-		OOG6_102544
Panther	1	1.100	-	-	LDO	PTHR45937
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R96
SonicParanoid	1	1.000	-	-		X3425
TreeFam	1	0.960	-	-
	16	15.740