Protein Alignment CG17486 and ASNSD1

DIOPT Version :10

• Sequence 1: NP_001036446.2
• Gene: CG17486 / 3355138
• FlyBaseID: FBgn0032997
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_061921.2
• Gene: ASNSD1 / 54529
• HGNCID: 24910
• Length: 643
• Species: Homo sapiens
• Alignment Length: 644
• Identity: 216/644 - (33%)
• Similarity: 319/644 - (49%)
• Gaps: 104/644 - (16%)

  Fly     1 MCGIFCSVVNNVPLNSFNISSALKVILKNRGPDVQDEVV---IDYCFGKILFAGFVLWQQGESVQ 62
            ||||.|||..:....|.::...|...||.|||:...:::   ::|   :.||:..||..:| .:.
Human     1 MCGICCSVNFSAEHFSQDLKEDLLYNLKQRGPNSSKQLLKSDVNY---QCLFSAHVLHLRG-VLT 61

  Fly    63 KQPVVEDD--FIFLFNGDIYNTSKPE-YMSDTTWIAERLAECRCKEQNILKILKRLEGPHCLIIY 124
            .|| |||:  .:||:||:|::..|.| ..:||..:...|:.|: .|..||.:...::||...|.|
Human    62 TQP-VEDERGNVFLWNGEIFSGIKVEAEENDTQILFNYLSSCK-NESEILSLFSEVQGPWSFIYY 124

  Fly   125 DKREQILYFSRDALGRNSLL--IERICNGFQLLS----TSHFEDKKISLELPPLGLFRVKLND-- 181
            ......|:|.||..||.|||  ...:...|.|.|    ||...::  ..|:|..||||:.|..
Human   125 QASSHYLWFGRDFFGRRSLLWHFSNLGKSFCLSSVGTQTSGLANQ--WQEVPASGLFRIDLKSTV 187

  Fly   182 LNSCV---LYPWQPLN---------NYSTQLLRNLD-----LAIGWKTAVESPMSPDWMLNCNPA 229
            ::.|:   ||||:.::         |..:|:..:|.     :|...|..:|.|:.|..|:....|
Human   188 ISGCIILQLYPWKYISRENIIEENVNSLSQISADLPAFVSVVANEAKLYLEKPVVPLNMMLPQAA 252

  Fly   230 FSYNFYEFQYIKNNVNLYKNLIDQSEIKYTLSILHTLLSDSIKNRVRNMAPFCRLCMQK------ 288
            ...:......:.....:.:..:....:|..:.....:||.::|.||        ||:.:
Human   253 LETHCSNISNVPPTREILQVFLTDVHMKEVIQQFIDVLSVAVKKRV--------LCLPRDENLTA 309

  Fly   289 LNISPPC-RHAKLCILFSGGLDCTILALLANQFVPVNEPIELINVAF-------------ESVKG 339
            ..:...| |.|.:.||||||:|..::|.||::.:|::|||:|:||||             |..|.
Human   310 NEVLKTCDRKANVAILFSGGIDSMVIATLADRHIPLDEPIDLLNVAFIAEEKTMPTTFNREGNKQ 374

  Fly   340 QNISE-------------------KLFDVPDRKTSLVSVNELKQLCPERCWNLLKVNVTRLELQQ 385
            :|..|                   |...||||.|....:.||:.:.|.|.||.:::||:..|||:
Human   375 KNKCEIPSEEFSKDVAAAAADSPNKHVSVPDRITGRAGLKELQAVSPSRIWNFVEINVSMEELQK 439

  Fly   386 HLTSRIKHLIYPLDTVLDESLGCAFWFASH------------CTHSTARVALIGSGADELFGGYT 438
            ...:||.|||.|||||||:|:|||.||||.            ...|.|:|.|.|.||||...||:
Human   440 LRRTRICHLIRPLDTVLDDSIGCAVWFASRGIGWLVAQEGVKSYQSNAKVVLTGIGADEQLAGYS 504

  Fly   439 RYRNSYSRCLGNDLERQLAVQNELERDWQRISARNLARDDRIIADTGKTARSPFIEENFVKFIRS 503
            |:|   .|...:.||   .:..|:..:..|||:|||.||||:|.|.||.||.||::||.|.|:.|
Human   505 RHR---VRFQSHGLE---GLNKEIMMELGRISSRNLGRDDRVIGDHGKEARFPFLDENVVSFLNS 563

  Fly   504 LEVYQKCCFGFPEGVGDKLLLRLYGYQIGLRDVVFLKKRAIQFGSRIANKKQNGSHQSD 562
            |.:::|.....|.|:|:||||||...::||.....|.|||:|||||||..::.....||
Human   564 LPIWEKANLTLPRGIGEKLLLRLAAVELGLTASALLPKRAMQFGSRIAKMEKINEKASD 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17486	NP_001036446.2	Gn_AT_II_novel	1..175	CDD:239735	60/185 (32%)
		Asn_synthase_B_C	296..548	CDD:467495	121/295 (41%)
ASNSD1	NP_061921.2	Gn_AT_II_novel	1..179	CDD:239735	60/185 (32%)
		Asn_synthase_B_C	320..608	CDD:467495	120/293 (41%)