Protein Alignment CG17486 and ASNS

DIOPT Version :9

• Sequence 1: NP_001036446.2
• Gene: CG17486 / 3355138
• FlyBaseID: FBgn0032997
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001339425.1
• Gene: ASNS / 440
• HGNCID: 753
• Length: 561
• Species: Homo sapiens
• Alignment Length: 611
• Identity: 134/611 - (21%)
• Similarity: 224/611 - (36%)
• Gaps: 164/611 - (26%)

  Fly     1 MCGIFCSVVNNVPLNSFNISSALKVILKNRGPDV-QDEVVIDY---CFG--KILFAGFVLWQQGE 59
            ||||: ::..:....|....||:|:  .:||||. :.|.|..|   |||  ::.....:...|..
Human     1 MCGIW-ALFGSDDCLSVQCLSAMKI--AHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPI 62

  Fly    60 SVQKQPVVEDDFIFL-FNGDIYNTSKP----EYMSDTTWIAERLAECRCK---EQNILKILKRLE 116
            .|:|.|     :::| :||:|||..|.    |:...|....|.:.....|   ||.|.    .|:
Human    63 RVKKYP-----YLWLCYNGEIYNHKKMQQHFEFEYQTKVDGEIILHLYDKGGIEQTIC----MLD 118

  Fly   117 GPHCLIIYDKREQILYFSRDALGRNSLLIERICNGFQLLSTSHFEDKKISLELPPLGLFRVKLND 181
            |....::.|...:.::..||..|...|        |:.::    ||..:::.....||..:|.:.
Human   119 GVFAFVLLDTANKKVFLGRDTYGVRPL--------FKAMT----EDGFLAVCSEAKGLVTLKHSA 171

  Fly   182 LNSCVLYPWQPLNNYSTQLLRNLDLAIGWKTAVESPMS-------PDWMLNCNPAFSYNFYEFQY 239
            .....:.|:.| .:|..     |||....|.|....:.       |...|..|....:..:|.:.
Human   172 TPFLKVEPFLP-GHYEV-----LDLKPNGKVASVEMVKYHHCRDVPLHALYDNVEKLFPGFEIET 230

  Fly   240 IKNNVNLYKNLIDQSEIKYTLSILHTLLSDSIKNRVRNMAPFCRLCMQKLNISPPCRHAKLCILF 304
            :|||                   |..|.::::|.|:..                   ..::..|.
Human   231 VKNN-------------------LRILFNNAVKKRLMT-------------------DRRIGCLL 257

  Fly   305 SGGLDCTIL-ALLANQF--VPVNEPIELINVAFESVKGQNISEKLFDVPD----RKTS------- 355
            |||||.::: |.|..|.  ..|..|::...:..|            |.||    ||.:
Human   258 SGGLDSSLVAATLLKQLKEAQVQYPLQTFAIGME------------DSPDLLAARKVADHIGSEH 310

  Fly   356 ---LVSVNELKQLCPERCWNLLKVNVT--RLELQQHLTSRIKHLIYPLDTVLDESLGCAFWFASH 415
               |.:..|..|...|..::|...::|  |..:..:|.|  |::....|:|
Human   311 YEVLFNSEEGIQALDEVIFSLETYDITTVRASVGMYLIS--KYIRKNTDSV-------------- 359

  Fly   416 CTHSTARVALIGSGADELFGGYTRYRNSYSRCLGNDLERQLAVQNELERDWQRISARNLARDDRI 480
                   |...|.|:|||..||..:..:.|.      |:   .:.|.||..:.:...::.|.||.
Human   360 -------VIFSGEGSDELTQGYIYFHKAPSP------EK---AEEESERLLRELYLFDVLRADRT 408

  Fly   481 IADTGKTARSPFIEENFVKFIRSLEVYQKCCFGFPEGVGDKLLLRLYGYQIGL--RDVVFLKKRA 543
            .|..|...|.||::..|..:..||....:    .|:...:|.|||.......|  :::::..|.|
Human   409 TAAHGLELRVPFLDHRFSSYYLSLPPEMR----IPKNGIEKHLLRETFEDSNLIPKEILWRPKEA 469

  Fly   544 IQFG-SRIANK-----KQNGSHQSDN 563
            ...| :.:.|.     ::...||.|:
Human   470 FSDGITSVKNSWFKILQEYVEHQVDD 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17486	NP_001036446.2	Gn_AT_II_novel	1..175	CDD:239735	47/187 (25%)
		Asn_Synthase_B_C	266..547	CDD:238949	64/301 (21%)
ASNS	NP_001339425.1	asnB	1..555	CDD:236513	134/611 (22%)
		Glutamine binding. /evidence=ECO:0000250	49..53		0/3 (0%)
		Glutamine binding. /evidence=ECO:0000250	75..77		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0367
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810