Protein Alignment Stlk and TAOK2

DIOPT Version :10

• Sequence 1: NP_001036442.1
• Gene: Stlk / 3355135
• FlyBaseID: FBgn0046692
• Length: 346
• Species: Drosophila melanogaster
• Sequence 2: XP_011544284.1
• Gene: TAOK2 / 9344
• HGNCID: 16835
• Length: 1242
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 98/347 - (28%)
• Similarity: 162/347 - (46%)
• Gaps: 62/347 - (17%)

  Fly    13 LEILKNGMIGTVYKAEDI-NNKCLAVKKVSMD--QPMEKLTLLFNEVLTVRRLQHRNINTIVSCF 74
            |..:.:|..|.||.|.|: |::.:|:||:|..  |..||...:..||..:::|:|.|......|:
Human    31 LREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCY 95

  Fly    75 LYKQYVYLTYKFMCFGNCEVLLKNVYTSGFPEVAIALILKDVLSALTYIHSEHYVHGSVRAKHIL 139
            |.:...:|..:: |.|:...||: |:.....||.||.:....|..|.|:||.:.:|..|:|.:||
Human    96 LREHTAWLVMEY-CLGSASDLLE-VHKKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNIL 158

  Fly   140 LS-PRKAVLSNFSYCQSFISQGEKKTFIFGSTVGIEKELYWTAPEVLYQNLSG-YTEKIDIYSIG 202
            || |....|.:|. ..|.::..       .|.||..   ||.||||:.....| |..|:|::|:|
Human   159 LSEPGLVKLGDFG-SASIMAPA-------NSFVGTP---YWMAPEVILAMDEGQYDGKVDVWSLG 212

  Fly   203 ITCCEMANGFQPFKDTELTYMYIEKVRGSLQVLLDKNSLLENQGSLS-LEHTNKRIARD---VIV 263
            |||.|:|....|                           |.|..::| |.|    ||::   |:.
Human   213 ITCIELAERKPP---------------------------LFNMNAMSALYH----IAQNESPVLQ 246

  Fly   264 NKSFSENFHQFVELCLNKNPLSRWAASKLMTHSFLKQCRNTS----LLDQLKDLGQKMS--KFKR 322
            :..:||.|..||:.||.|.|..|..:..|:.|.|:.:.|..:    |:.:.||..:::.  ::::
Human   247 SGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDAVRELDNLQYRK 311

  Fly   323 NEHEIFSDA---RGSHNPQPND 341
            .:..:|.:|   .|:..|:..:
Human   312 MKKILFQEAPNGPGAEAPEEEE 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stlk	NP_001036442.1	PK_STRAD	7..312	CDD:270856	92/311 (30%)
TAOK2	XP_011544284.1	STKc_TAO2	12..319	CDD:270804	95/331 (29%)
		Smc	<474..>810	CDD:440809