DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stlk and strada

DIOPT Version :9

Sequence 1:	NP_001036442.1	Gene:	Stlk / 3355135	FlyBaseID:	FBgn0046692	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_021325312.1	Gene:	strada / 334550	ZFINID:	ZDB-GENE-030131-6482	Length:	442	Species:	Danio rerio

Alignment Length:	350	Identity:	115/350 - (32%)
Similarity:	170/350 - (48%)	Gaps:	34/350 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SDYKLLEILKNGMIG------TVYKAEDINNKCLAVKKVSMDQ-PMEKLTLLFNEVLTVRRLQHR 65
            |.|:|..::..|:..      .|||.   ..:.:|::::.:|. ..:.::.|..|:...:...|.
Zfish    73 SAYELRNVIGRGLESLMTVNLAVYKP---TGEYVAIRRIDLDSCANDMVSYLQGELRVSKLFHHP 134

  Fly    66 NINTIVSCFLYKQYVYLTYKFMCFGNCEVLLKNVYTSGFPEVAIALILKDVLSALTYIHSEHYVH 130
            .|....|.|:.:..:::...||.:|:...|:...:|.|..|..||.||..||.||.|||...|||
Zfish   135 CILPYKSVFIAENELWVITPFMAYGSARDLIITHFTDGLNEQTIAYILLGVLRALEYIHQMGYVH 199

  Fly   131 GSVRAKHILLS-PRKAVLSNFSYCQSFISQGEKKTFIFGSTVGIEKELYWTAPEVLYQNLSGYTE 194
            .||:|.|||:| ..:..||......|.|..|::...:........|.|.|.:||||.|||.||..
Zfish   200 RSVKASHILISADGQMFLSGLRSIFSLIRHGQRARVVHDFPQYSVKVLPWLSPEVLQQNLQGYDF 264

  Fly   195 KIDIYSIGITCCEMANGFQPFKDTELTYMYIEKVRGSLQVLLD------------------KNSL 241
            :.||||:|||.||:|||..||||...|.|.:||:.|::..|||                  .:.:
Zfish   265 RSDIYSLGITACELANGHVPFKDMPATQMLLEKLNGTVPCLLDTTTIPPEELSMKPSRSGADSGI 329

  Fly   242 LENQGSLSLEHTNKRIARDVIVN---KSFSENFHQFVELCLNKNPLSRWAASKLMTHSFLKQC-- 301
            .|..|:....|||...:.....|   ::||.:||.||||||.::|..|.:||.|:.|||.||.
Zfish   330 CEGPGAGGARHTNGEPSSSSGGNPYSRTFSSHFHAFVELCLQRDPEKRPSASSLIGHSFFKQIKR 394

  Fly   302 RNTSLLDQLKDLGQKMSKFKRNEHE 326
            |.:..|.:|......:|.....:|:
Zfish   395 RPSEALPELLRPVSPISSLDSMQHQ 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stlk	NP_001036442.1	PK_STRAD	7..312	CDD:270856	113/334 (34%)
Stlk	NP_001036442.1	S_TKc	10..298	CDD:214567	106/316 (34%)
strada	XP_021325312.1	PKc_like	76..406	CDD:328722	111/332 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	157	1.000	Domainoid score	I4119
eggNOG	1	0.900	-	-		E1_KOG0582
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12448
Inparanoid	1	1.050	162	1.000	Inparanoid score	I4195
OMA	1	1.010	-	-		QHG52849
OrthoDB	1	1.010	-	-		D421757at33208
OrthoFinder	1	1.000	-	-		FOG0003031
OrthoInspector	1	1.000	-	-		otm24912
orthoMCL	1	0.900	-	-		OOG6_108116
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4773
SonicParanoid	1	1.000	-	-		X2021
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.810