back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Stlk and Pak5

DIOPT Version :10

Sequence 1:	NP_001036442.1	Gene:	Stlk / 3355135	FlyBaseID:	FBgn0046692	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001101251.1	Gene:	Pak5 / 311450	RGDID:	1312009	Length:	718	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	83/296 - (28%)
Similarity:	137/296 - (46%)	Gaps:	51/296 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 EILKN------GMIGTVYKA-EDINNKCLAVKKVSMDQPMEKLTLLFNEVLTVRRLQHRNINTIV 71
            |.|.|      |..|.|..| |....|.:||||:.: :..::..||||||:.:|...|.|:..:.
  Rat   446 EYLDNFIKIGEGSTGIVCIATEKHTGKQVAVKKMDL-RKQQRRELLFNEVVIMRDYHHDNVVDMY 509

  Fly    72 SCFLYKQYVYLTYKFMCFGNCEVLLKNVYT-SGFPEVAIALILKDVLSALTYIHSEHYVHGSVRA 135
            :.:|....:::..:|:..|    .|.::.| :...|..||.:...||.||:|:|::..:|..:::
  Rat   510 NSYLVGDELWVVMEFLEGG----ALTDIVTHTRMNEEQIATVCLSVLKALSYLHNQGVIHRDIKS 570

  Fly   136 KHILL-SPRKAVLSNFSYCQSFISQGEKKTFIFGSTVGIEKELYWTAPEVLYQNLSGYTEKIDIY 199
            ..||| |..:..||:|.:|.....:..|:..:.|:.       ||.||||:  :...|..::||:
  Rat   571 DSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTP-------YWMAPEVI--SRLPYGTEVDIW 626

  Fly   200 SIGITCCEMANGFQP-FKDTELTYMYIEKVRGSLQVLLDKNSLLENQGSLSLEHTNKRIARDVIV 263
            |:||...||.:|..| |.:..|..|  .::|.||.                     .|: :|:
  Rat   627 SLGIMVIEMIDGEPPYFNEPPLQAM--RRIRDSLP---------------------PRV-KDL-- 665

  Fly   264 NKSFSENFHQFVELCLNKNPLSRWAASKLMTHSFLK 299
             ...|.....|::|.|.:.|..|..|.:|:.|.|||
  Rat   666 -HKVSSMLRGFLDLMLVREPSQRATAQELLGHPFLK 700

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.