Protein Alignment Stlk and MAP4K1

DIOPT Version :10

• Sequence 1: NP_001036442.1
• Gene: Stlk / 3355135
• FlyBaseID: FBgn0046692
• Length: 346
• Species: Drosophila melanogaster
• Sequence 2: XP_011524706.1
• Gene: MAP4K1 / 11184
• HGNCID: 6863
• Length: 861
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 89/325 - (27%)
• Similarity: 149/325 - (45%)
• Gaps: 64/325 - (19%)

  Fly    10 YKLLEILKNGMIGTVYKAED-INNKCLAVKKVSMDQPMEKLTLLFNEVLTVRRLQHRNINTIVSC 73
            |.||:.|..|..|.|:||.| ::...:|:|.|.| :|.:.::.|..|:|.::..:|.||......
Human    17 YDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKM-EPDDDVSTLQKEILILKTCRHANIVAYHGS 80

  Fly    74 FLYKQYVYLTYKFMCFGNCEVLLKNVY--TSGFPEVAIALILKDVLSALTYIHSEHYVHGSVRAK 136
            :|:.|.:::..:|...|:    |:::|  |....|:.|:.:.::||..|.|:||:..:|..::..
Human    81 YLWLQKLWICMEFCGAGS----LQDIYQVTGSLSELQISYVCREVLQGLAYLHSQKKIHRDIKGA 141

  Fly   137 HILLSPRKAVLSNFSYCQSFISQGEKKTFIFGSTVGIEKEL----------YWTAPEVLYQNL-S 190
            :||::                ..||.:...||.:..|...|          ||.||||....| .
Human   142 NILIN----------------DAGEVRLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKG 190

  Fly   191 GYTEKIDIYSIGITCCEMANGFQPFKDTELTYMYIEKVRGSLQVLLDKNSLLENQGSLSLEHTNK 255
            ||.|..||:|:|||..|:|....|..|..           .|:||.    |:...|     :...
Human   191 GYNELCDIWSLGITAIELAELQPPLFDVH-----------PLRVLF----LMTKSG-----YQPP 235

  Fly   256 RIARDVIVNKSFSENFHQFVELCLNKNPLSRWAASKLMTHSFLKQCRNT-----SLLDQLKDLGQ 315
            |:..    ...:|..||.|:::.|.|:|..|.:|:|:::|..:.|....     .|||:||:.|:
Human   236 RLKE----KGKWSAAFHNFIKVTLTKSPKKRPSATKMLSHQLVSQPGLNRGLILDLLDKLKNPGK 296

  Fly   316  315
            Human   297  296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stlk	NP_001036442.1	PK_STRAD	7..312	CDD:270856	87/320 (27%)
MAP4K1	XP_011524706.1	STKc_MAP4K3_like	16..274	CDD:270788	82/301 (27%)
		CNH	540..847	CDD:214481