DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stlk and Oxsr1

DIOPT Version :9

Sequence 1:	NP_001036442.1	Gene:	Stlk / 3355135	FlyBaseID:	FBgn0046692	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_001346511.1	Gene:	Oxsr1 / 108737	MGIID:	1917378	Length:	527	Species:	Mus musculus

Alignment Length:	342	Identity:	89/342 - (26%)
Similarity:	165/342 - (48%)	Gaps:	55/342 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SNNISDYKLLEILKNGMIGTVYKAEDINNK-CLAVKKVSMDQPMEKLTLLFNEVLTVRRLQHRNI 67
            |.|..||:|.|::.:|....|..|.....| .:|:|::::::....:..|..|:..:.:..|.||
Mouse    11 SINRDDYELQEVIGSGATAVVQAAYCAPKKERVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNI 75

  Fly    68 NTIVSCFLYKQYVYLTYKFMCFGNCEVLLKNVYTSG------FPEVAIALILKDVLSALTYIHSE 126
            .:..:.|:.|..::|..|.:..|:...::|::...|      ..|..||.||::||..|.|:|..
Mouse    76 VSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEPTIATILREVLEGLEYLHKN 140

  Fly   127 HYVHGSVRAKHILLSPRKAV-LSNFSYCQSFISQG-------EKKTFIFGSTVGIEKELYWTAPE 183
            ..:|..|:|.:|||....:| :::|. ..:|::.|       .:|||: |:..       |.|||
Mouse   141 GQIHRDVKAGNILLGEDGSVQIADFG-VSAFLATGGDITRNKVRKTFV-GTPC-------WMAPE 196

  Fly   184 VLYQNLSGYTEKIDIYSIGITCCEMANGFQPFKDTELTYMYIEKVRGSLQVLLDKNSLLENQGSL 248
            |:.| :.||..|.||:|.|||..|:|.|..|:      :.|     ..::||:           |
Mouse   197 VMEQ-VRGYDFKADIWSFGITAIELATGAAPY------HKY-----PPMKVLM-----------L 238

  Fly   249 SLEHTNKRI---ARDVIVNKSFSENFHQFVELCLNKNPLSRWAASKLMTHSFLKQCRN-----TS 305
            :|::....:   .:|..:.|.:.::|.:.:.|||.|:|..|..|::|:.|.|.::.:|     ..
Mouse   239 TLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQEK 303

  Fly   306 LLDQLKDLGQKMSKFKR 322
            :|.:...:.::..|.:|
Mouse   304 ILQRAPTISERSKKVRR 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stlk	NP_001036442.1	PK_STRAD	7..312	CDD:270856	85/327 (26%)
Stlk	NP_001036442.1	S_TKc	10..298	CDD:214567	81/305 (27%)
Oxsr1	NP_001346511.1	STKc_OSR1_SPAK	15..291	CDD:270787	82/307 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	313..356		2/8 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	392..429
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0582
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810