Protein Alignment Stlk and BUB1B-PAK6

DIOPT Version :10

• Sequence 1: NP_001036442.1
• Gene: Stlk / 3355135
• FlyBaseID: FBgn0046692
• Length: 346
• Species: Drosophila melanogaster
• Sequence 2: NP_001122100.1
• Gene: BUB1B-PAK6 / 106821730
• HGNCID: 52276
• Length: 681
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 85/303 - (28%)
• Similarity: 144/303 - (47%)
• Gaps: 43/303 - (14%)

  Fly    19 GMIGTVYKA-EDINNKCLAVKKVSMDQPMEKLTLLFNEVLTVRRLQHRNINTIVSCFLYKQYVYL 82
            |..|.|..| |..:.:.:|||.:.: :..::..||||||:.:|..||.|:..:...:|..:.:::
Human   416 GSTGIVCLAREKHSGRQVAVKMMDL-RKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELWV 479

  Fly    83 TYKFMCFGNCEVLLKNVYTSGFPEVAIALILKDVLSALTYIHSEHYVHGSVRAKHILLS-PRKAV 146
            ..:|:..|....::..|..:   |..||.:.:.||.||.|:|::..:|..:::..|||: ..:..
Human   480 LMEFLQGGALTDIVSQVRLN---EEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVK 541

  Fly   147 LSNFSYCQSFISQGEKKTFIFGSTVGIEKELYWTAPEVLYQNLSGYTEKIDIYSIGITCCEMANG 211
            ||:|.:|........|:..:.|:.       ||.||||:.::|  |..::||:|:||...||.:|
Human   542 LSDFGFCAQISKDVPKRKSLVGTP-------YWMAPEVISRSL--YATEVDIWSLGIMVIEMVDG 597

  Fly   212 FQP-FKDTELTYMYIEKVRGSLQVLLDKNSLLENQGSLSLEHTNKRIARDVIVNKSFSENFHQFV 275
            ..| |.|:.:..|  :::|.|....| |||           |....:.||             |:
Human   598 EPPYFSDSPVQAM--KRLRDSPPPKL-KNS-----------HKVSPVLRD-------------FL 635

  Fly   276 ELCLNKNPLSRWAASKLMTHSFLKQCRNTSLLDQLKDLGQKMS 318
            |..|.::|..|..|.:|:.|.||.|......|..|..|.:|.:
Human   636 ERMLVRDPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQT 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stlk	NP_001036442.1	PK_STRAD	7..312	CDD:270856	83/295 (28%)
BUB1B-PAK6	NP_001122100.1	PBD	11..67	CDD:395634
		STKc_PAK6	385..681	CDD:270821	85/303 (28%)