DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stlk and stradb

DIOPT Version :9

Sequence 1:	NP_001036442.1	Gene:	Stlk / 3355135	FlyBaseID:	FBgn0046692	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_009300390.1	Gene:	stradb / 100536950	ZFINID:	ZDB-GENE-130826-1	Length:	424	Species:	Danio rerio

Alignment Length:	392	Identity:	112/392 - (28%)
Similarity:	171/392 - (43%)	Gaps:	68/392 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SNNISDYKLLEILKNGM--IGTVYKAEDI-NNKCLAVKKVSMDQPME-KLTLLFNEVLTVRRLQH 64
            |.:.:.|:||..|..|.  :..|..|... :.:.:|||..::|:..| :|..|.||||..||.:|
Zfish    52 STDSAHYQLLSPLGRGFNNLSHVSVARHTPSGRLVAVKNTNLDECTEDELLQLMNEVLLSRRFRH 116

  Fly    65 RNINTIVSCFLYKQYVYLTYKFMCFGNCEVLLKNVYTSGFPEVAIALILKDVLSALTYIHSEHYV 129
            .|:.|....|.....:::....|.:|:.:.||::.:..|..|..:|.:|..||.||.|:|...||
Zfish   117 PNLLTSRLVFSSCCQLWVLAPLMSYGSADSLLRSYFPDGMSESLMAYLLYGVLRALEYLHHMGYV 181

  Fly   130 HGSVRAKHILLSPR-KAVLSNFSYCQSFISQGEKKTFIFGSTVGIEKELYWTAPEVLYQNLSGYT 193
            |..|:|.|:|||.. :..||......|.:..|::...:|.........|.|.:||:|.|:|.||.
Zfish   182 HRGVKASHVLLSAEGRVCLSGLQSVYSLMKDGKRMRAVFDMPQHSPSLLPWLSPELLRQDLHGYG 246

  Fly   194 EKIDIYSIGITCCEMANGFQPFKDTELTYMYIEKVRGSLQVLLDKNSL-LENQGSLSLEHT--NK 255
            .|.||||:||..||:.:|..||:|...|.|.::|:|||...|||.... |...|:|.:..:  :.
Zfish   247 VKSDIYSLGIVACELVSGRVPFQDMPPTLMLLQKLRGSHCCLLDVPPYPLGGMGALKVSRSGVDS 311

  Fly   256 RIARDVIVN----------------KSFSENFHQFVELCLNKNPLSRWAASKLMTHSFLKQCRNT 304
            .|...|...                |:.|...|..|:|||.:.|..|.:|:.|:.|.|.:|
Zfish   312 GIGESVATGSLTRTATAERPQSPAPKNHSATLHNLVQLCLQQQPERRPSATALLNHPFFRQ---- 372

  Fly   305 SLLDQLKDLGQKMSKFKRNEHEIF-------------SDARGSH------------NPQPNDTIW 344
                           .|::..:.|             .|...|.            :|:|.|.:|
Zfish   373 ---------------VKKHTRDSFLSLMYPAVPVSCPPDTPPSQTPTQTCNTPSPTDPEPEDGLW 422

  Fly   345 KF 346
            .|
Zfish   423 DF 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stlk	NP_001036442.1	PK_STRAD	7..312	CDD:270856	102/328 (31%)
Stlk	NP_001036442.1	S_TKc	10..298	CDD:214567	100/311 (32%)
stradb	XP_009300390.1	PKc_like	59..387	CDD:328722	103/346 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	157	1.000	Domainoid score	I4119
eggNOG	1	0.900	-	-		E1_KOG0582
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	162	1.000	Inparanoid score	I4195
OMA	1	1.010	-	-		QHG52849
OrthoDB	1	1.010	-	-		D421757at33208
OrthoFinder	1	1.000	-	-		FOG0003031
OrthoInspector	1	1.000	-	-		otm24912
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2021
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.840