DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stlk and stk39

DIOPT Version :9

Sequence 1:	NP_001036442.1	Gene:	Stlk / 3355135	FlyBaseID:	FBgn0046692	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_017953089.2	Gene:	stk39 / 100488948	XenbaseID:	XB-GENE-1012528	Length:	609	Species:	Xenopus tropicalis

Alignment Length:	367	Identity:	93/367 - (25%)
Similarity:	168/367 - (45%)	Gaps:	77/367 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 YKLLEILKNGMIGTVYKAEDINNKC------LAVKKVSMDQPMEKLTLLFNEVLTVRRLQHRNIN 68
            |:|.|::.:|....|..|     .|      :|:|::::::....:..|..|:..:.:..|.||.
Frog   128 YELQEVIGSGATAVVQAA-----LCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNIV 187

  Fly    69 TIVSCFLYKQYVYLTYKFMCFGNCEVLLKNVYTSG------FPEVAIALILKDVLSALTYIHSEH 127
            |..:.|:.|:.::|..|.:..|:...::|:|...|      ..|..||.|||:||..|.|:|...
Frog   188 TYYTSFVVKEELWLVMKLLSGGSMLDIIKHVVGRGEHKNGVLEESIIATILKEVLEGLDYLHRNG 252

  Fly   128 YVHGSVRAKHILLSPRKAV-LSNFSYCQSFISQG-------EKKTFIFGSTVGIEKELYWTAPEV 184
            .:|..::|.:|||....:| :::|. ..||::.|       .:|||: |:..       |.||||
Frog   253 QIHRDLKAGNILLGEDGSVQIADFG-VSSFLATGGDVTRNKVRKTFV-GTPC-------WMAPEV 308

  Fly   185 LYQNLSGYTEKIDIYSIGITCCEMANGFQPFKDTELTYMYIEKVRGSLQVLLDKNSLLENQGSLS 249
            :.| :.||..|.|::|.|||..|:|.|..|:      :.|     ..::||:           |:
Frog   309 MEQ-VRGYDFKADMWSFGITAIELATGAAPY------HKY-----PPMKVLM-----------LT 350

  Fly   250 LEH---TNKRIARDVIVNKSFSENFHQFVELCLNKNPLSRWAASKLMTHSFLKQCRN-----TSL 306
            |::   |.:....|..:.:.:.::|.:.:.|||.|:|..|..|::|:...|.::.:|     ..|
Frog   351 LQNDPPTLETGVEDKEMMRKYGKSFRKLISLCLQKDPSKRPTAAELLKCKFFQKSKNREYLIEKL 415

  Fly   307 LDQLKDLGQKMSKFKRNEHEIFSDARGS----HNPQPNDTIW 344
            |.:..::..:..|.:|        ..||    |..:..|..|
Frog   416 LIKTPNIALRGKKVRR--------VPGSSGHLHKNEDGDWEW 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stlk	NP_001036442.1	PK_STRAD	7..312	CDD:270856	86/329 (26%)
Stlk	NP_001036442.1	S_TKc	10..298	CDD:214567	82/310 (26%)
stk39	XP_017953089.2	STKc_OSR1_SPAK	126..402	CDD:270787	82/310 (26%)
stk39	XP_017953089.2	OSR1_C	516..573	CDD:403428
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910