Protein Alignment CG17528 and RP1L1

DIOPT Version :9

• Sequence 1: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: NP_849188.4
• Gene: RP1L1 / 94137
• HGNCID: 15946
• Length: 2400
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 86/405 - (21%)
• Similarity: 151/405 - (37%)
• Gaps: 108/405 - (26%)

  Fly   136 NTPTADHIKKRIPS-SRTPT----RKALRIKFYRNGDRFYPGITIPVSNERYRSFERLFEDLTRL 195
            |.....|.:..:|| :|||:    ..|.:|.|.:.||..:.|:.:.|....:::|..|.::|:
Human     7 NAQAPSHRECFLPSVARTPSVTKVTPAKKITFLKRGDPRFAGVRLAVHQRAFKTFSALMDELS-- 69

  Fly   196 LEENVKIPGAVRTIYNLCG-KKITSLDELEDGQSYVCSCNNENFKKVEYNTGSQPLSNLPLSNSR 259
              :.|.:...||::....| ..:::|::||||..|:||      .|....|.|.|
Human    70 --QRVPLSFGVRSVTTPRGLHSLSALEQLEDGGCYLCS------DKKPPKTPSGP---------- 116

  Fly   260 SNSHRLAKCRPSSPLKNGL--LAGSSPFPACGGGTGNGSPLIASRLSDRVTVVHPRIVTLIRSGT 322
                  .:.:..:|....|  :.|....|    ||.          |.|.::..||.:.||:: .
Human   117 ------GRPQERNPTAQQLRDVEGQREAP----GTS----------SSRKSLKTPRRILLIKN-M 160

  Fly   323 KPRRIMRLLLNKRNSPSFDHVLTAITQVVRLDTGYVRKVFTLSGIPVVRLSDFFGSDDVFFAYGT 387
            .||....::|:.||:.:....|...:.::|..   |::::|.||..|..|.....|..|....|.
Human   161 DPRLQQTVVLSHRNTRNLAAFLGKASDLLRFP---VKQLYTTSGKKVDSLQALLHSPSVLVCAGH 222

  Fly   388 ERINTAEDFKLEAEEQRAINVIRKTMRTT--GTTCK------GPK---------------PKMPI 429
            |...|.           |:...|::...|  |.|.:      |||               |::|.
Human   223 EAFRTP-----------AMKNARRSEAETLSGLTSRNKNGSWGPKTKPSVIHSRSPPGSTPRLPE 276

  Fly   430 KSKKVYPPLVDSEPFKAETTPEDDRHAALLTSTGME----INELPSNIRNTYSLGRIIGDGNFAI 490
            :.....||:..:.....:.||.  :...|:....|:    :||                ||:.::
Human   277 RPGPSNPPVGPAPGRHPQDTPA--QSGPLVAGDDMKKKVRMNE----------------DGSLSV 323

  Fly   491 VFKIKHRQTGHSYAL 505
            ..|::....|....|
Human   324 EMKVRFHLVGEDTLL 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711	24/95 (25%)
		DCX	308..396	CDD:214711	22/87 (25%)
		PKc_like	477..734	CDD:304357	5/29 (17%)
		S_TKc	477..734	CDD:214567	5/29 (17%)
RP1L1	NP_849188.4	DCX	34..111	CDD:176357	22/86 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..152		14/83 (17%)
		UBQ	152..226	CDD:320785	20/77 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	230..310		14/81 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	444..1064
		Herpes_ICP4_C	561..>904	CDD:332854
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1188..1251
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1275..1501
		3 X 16 AA approximate tandem repeats of T-E-E-G-L-Q-E-E-G-V-Q-L-E-E-T-K	1292..1342
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1697..2400
		Na_Ca_ex	<1697..1935	CDD:332332
		Na_Ca_ex	<1824..2121	CDD:332332
		25 X 16 AA approximate tandem repeats of [ED]-[AT]-[PQ]-[ED]-[AVT]-E-[GKE]-[ED]-[AMT]-Q-[EPK]- [EAT]-[TSELP]-[EG]-[EGSQDI]-[AVIE]	1836..2244
		Na_Ca_ex	<2020..>2260	CDD:332332

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3757
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810