DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and TDA1

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_014019.1	Gene:	TDA1 / 855336	SGDID:	S000004905	Length:	586	Species:	Saccharomyces cerevisiae

Alignment Length:	400	Identity:	105/400 - (26%)
Similarity:	162/400 - (40%)	Gaps:	132/400 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   413 MRTTGTTCKGPKPKMPIKSKKVYPPL----VDSEPFKAETTPEDDRHAALLTSTGMEINELPSNI 473
            |.|..::....:.::|  .:|.:|.|    .|::.||.:                        .:
Yeast     1 MTTASSSASQLQQRLP--EEKPWPQLSGSNADAQTFKCK------------------------YV 39

  Fly   474 RNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAE----------VRVMK 528
            .|..||    |||||::|.:..:..|...||:|:|.|...|.|...|..|          :|.|:
Yeast    40 TNHNSL----GDGNFSVVKECMNIHTKDLYAMKLIKKQTVKNKIQLIQREFDLLRSISEKIRDME 100

  Fly   529 KLN---------HPHIISLILSVDQNTNMYLVLEYVSGGDLFDAI---------TQVTRFSENQS 575
            |.|         |.||:.|....:...|:.|:.:....|||::.|         ||||.:
Yeast   101 KKNEHSLDIFEGHHHILQLFDYFETADNIVLITQLCQKGDLYEKIVENQCLDLETQVTSY----- 160

  Fly   576 RIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKL-----------DEHGN------VLELKLADFG 623
               ...|.:.:.:|||.||||||:|.||:|.:|           :.||:      ..:|.|||||
Yeast   161 ---CACLVSVLEFLHSQGIVHRDLKAENVLFRLRVNENEKNLQGEHHGDFKYDLLAHDLVLADFG 222

  Fly   624 LACEVN----DLLYAVCGTPTYVAPEILL----------EVG----YGLKIDVWAAGIILYILLC 670
            ||.|.|    :.|....||.:|:||||:.          :||    ||..:|:||.|::.|.:..
Yeast   223 LAAEYNTSKVNSLKEFVGTISYIAPEIVKCKGVGEMTPDQVGKLDKYGCPVDIWALGVLTYFMAF 287

  Fly   671 GFPPFVAPDNQQEPLFDAIISGIY-----EFPDP----YWSDIGDGVRDLIANMLQA----DPDV 722
            |:.||....:.:  ..:.|....|     ...||    :|            |.:|.    ||.|
Yeast   288 GYTPFDCTTDDE--TLECISKCDYYVDEQMMHDPKYEQFW------------NFVQCCFTIDPAV 338

  Fly   723 RFTSEDILDH 732
            |.:::::..|
Yeast   339 RRSAKNLKQH 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	94/331 (28%)
		S_TKc	477..734	CDD:214567	94/331 (28%)
TDA1	NP_014019.1	STKc_CAMK	37..350	CDD:270687	95/361 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810