DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and CMK2

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_014626.1	Gene:	CMK2 / 854144	SGDID:	S000005376	Length:	447	Species:	Saccharomyces cerevisiae

Alignment Length:	283	Identity:	99/283 - (34%)
Similarity:	158/283 - (55%)	Gaps:	19/283 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   466 INEL---PSNI--RNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKE---HYIDA 522
            ||:|   |.:.  |..|..||.:|.|:|.:|.:.:...|....|:||:.|...:|..   ..:..
Yeast    31 INKLSGQPESYVNRTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYE 95

  Fly   523 EVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSE-NQSRIMIRHLGAAM 586
            |:.:::||:||:|:|.....:.....|:|.:..:||:|||.|....:|:| :...|:::.|| |:
Yeast    96 ELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILG-AV 159

  Fly   587 TYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEV---NDLLYAVCGTPTYVAPEILL 648
            .|:||..:||||:||||:|. :|:..| ..|.:||||:|.::   .||:|...|:..|||||:|.
Yeast   160 EYMHSKNVVHRDLKPENVLY-VDKSEN-SPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLT 222

  Fly   649 EVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIY--EFPDPYWSDIGDGVRDL 711
            :.|:|...|:|:.|:|.|.||||:.||:|  ...|...:...:..|  .|..|||.:|...|:..
Yeast   223 QDGHGKPCDIWSIGVITYTLLCGYSPFIA--ESVEGFMEECTASRYPVTFHMPYWDNISIDVKRF 285

  Fly   712 IANMLQADPDVRFTSEDILDHSW 734
            |...|:.:|..|.|:.::||..|
Yeast   286 ILKALRLNPADRPTATELLDDPW 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	93/265 (35%)
		S_TKc	477..734	CDD:214567	93/265 (35%)
CMK2	NP_014626.1	STKc_CAMK	46..308	CDD:270687	93/266 (35%)
CMK2	NP_014626.1	S_TKc	47..309	CDD:214567	94/267 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810