Protein Alignment CG17528 and NNK1

DIOPT Version :10

• Sequence 1: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: NP_012750.1
• Gene: NNK1 / 853683
• SGDID: S000001654
• Length: 928
• Species: Saccharomyces cerevisiae
• Alignment Length: 681
• Identity: 154/681 - (22%)
• Similarity: 265/681 - (38%)
• Gaps: 161/681 - (23%)

  Fly    19 SSLQASPSATSPQS---------------VPSKANVVTEASIIEKTN-QPHNVQEDNNYNRDCDS 67
            ||..|||.:.||.|               :|:.......|:..:... :|..:     |..:.:.
Yeast    24 SSGTASPISDSPASNRSYGRDLRGLMGIDIPANEPAFNRANSSDTIYFRPKKI-----YKMEHEH 83

  Fly    68 PESSSSEQDKELDDLRNLHSSSL-----TNSVVVGKSTGSLNGVYSI----------TSVTSE-T 116
            |..|:..|.:......::.||.:     |:.:.:|...|: ..:|:|          |.:.:| .
Yeast    84 PSRSTLVQLQTRSQPDDVASSQVNPEGGTDDLELGDPCGN-QSLYTIGAEYVPDLDFTKLVNEWQ 147

  Fly   117 KTLESVVT-TNSASGSACLSNTPTADHIKKRIPSSRTPTRKALRIKF-YRNGDRFYPGITIPVSN 179
            |:.|.:.. .:||:....:.::...::.....|.:.....|..|..| ..|.|...|..:|
Yeast   148 KSTEDLYEFRSSATPQVQIKDSGKGNYELWSSPDAILTQNKLRRDSFSQENSDSLSPEDSI---- 208

  Fly   180 ERYRSFERLFEDLTRLLEENVK---IPGAVRTIYNLCGKKITSLDELEDGQSYVCSCNNENFKKV 241
                        |:|.|...||   :|...:.|:.    .:::| |.|...||..|.||.
Yeast   209 ------------LSRNLHSKVKPIPLPRNSQQIFT----PLSNL-EAERRSSYTTSSNNN----- 251

  Fly   242 EYNTGSQPLSNLPLSNSRSNSHRLAKCRPSSPLKNGLLAGSSPFPACGGGTGNGSPL------IA 300
                          |.:::|....||.:.|.|.:      ||..||  ....|.|.|      ..
Yeast   252 --------------SITQNNKFSFAKLKYSLPTQ------SSAVPA--SFDSNASSLNFLPTTTL 294

  Fly   301 SRLSDRVTVVHPR-IVTLIRSGTKPRRIMRLLLNKR------NSPSFDH-VLTAITQVVRLDTGY 357
            |.||:  ..:.|. ::.||:.  .||..:.|...:|      ::||.|: .:.::.:...|.:.
Yeast   295 STLSE--LQISPNDMMDLIQK--LPRNFLNLPYTQRKKVIIEHAPSHDYKAMMSLVKKFMLTSS- 354

  Fly   358 VRKVFTLSGIP-VVRLSDFFGSDDVFFAYGTERINTAEDFKLEA---EEQRAINVIRKTMRTTGT 418
             |..|:|:|.. ...:|....:||...:..|.  |.:.|..:..   :..|..::..:.:.:.
Yeast   355 -RSNFSLAGFANNASVSQATANDDNINSRNTP--NNSNDTYVNTRPLQRSRHGSIASQFLSSF-- 414

  Fly   419 TCKGPKPKMPIKSKKVYPPLVDSEPFKAETTPEDDRHAALLTSTGMEINELPSNIRNTYSLGRII 483
                 .|.|...:|....||..|....|.  |:|         .||||        ..:.||:||
Yeast   415 -----SPSMTSIAKMNSNPLSGSAGGSAR--PDD---------KGMEI--------LGHRLGKII 455

  Fly   484 GDGNFAIVFKIKHRQTGHSYALKIIDKNKCKG----KEHYIDAEVRVMKKLNHPHIISLI-LSVD 543
            |.|.:.|:.:....:||....:||:   |.||    |:|.: .||.:.:.|.|..|:.|: ..:|
Yeast   456 GFGAWGIIRECFDIETGVGRVIKIV---KFKGHQNIKKHVL-REVAIWRTLKHNRILPLLDWKLD 516

  Fly   544 QNTNMYLVLEYVSGGDLFDAITQVTRFSEN------QSRIMI---RHLGAAMTYLHSMGIVHRDI 599
            .|..||.:.|.::.|.|:|.:.....|..:      :.|:.|   ..|.:|:.|:||..|||.||
Yeast   517 DNYAMYCLTERINDGTLYDLVISWDEFKRSKIPFAERCRLTIFLSLQLLSALKYMHSKTIVHGDI 581

  Fly   600 KPENLLVKLDEHGNVLELKLADFGLACEVND 630
            |.||.|::.:...:..::.|.|||::|..::
Yeast   582 KLENCLLQKEGKKSDWKVFLCDFGMSCHFDE 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX1	156..239	CDD:340526	22/86 (26%)
		Ubl1_cv_Nsp3_N-like	309..392	CDD:475130	19/91 (21%)
		Protein Kinases, catalytic domain	477..734	CDD:473864	52/168 (31%)
NNK1	NP_012750.1	PKc	455..>613	CDD:270622	49/162 (30%)
		Protein Kinases, catalytic domain	<817..864	CDD:473864
		Pkinase	<821..913	CDD:459660