DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and RCK1

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_011357.1	Gene:	RCK1 / 852719	SGDID:	S000003126	Length:	512	Species:	Saccharomyces cerevisiae

Alignment Length:	404	Identity:	120/404 - (29%)
Similarity:	185/404 - (45%)	Gaps:	89/404 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   383 FAYGTERINTAEDFKLEAEEQRAINVIRKTMRTTGTTCKGPKPKMPIKSKKVYPPLVDSEPFKAE 447
            ||.|..|.:.:.||.:.:.:                            |:|       ||....|
Yeast    47 FASGCRRSSLSVDFNVTSSD----------------------------SEK-------SEQSCLE 76

  Fly   448 TTPEDDRHAALLTSTGMEINE--------------LPSNIR-NTYSLGRIIGDGNFAIVFKIKHR 497
            ...::|.:...:.||.::::|              .|..:. :.|.|...||:|.|:.|||....
Yeast    77 NNSQEDEYFCDIFSTELKLDETSNKSTDYSSSNHQYPEQLELHNYKLLNKIGEGAFSRVFKAVGI 141

  Fly   498 QTGHS--YALKIIDKNK------CKGKEHY-------IDAEVRVMKKL--NHPHIISLILSVDQN 545
            .|...  .|:|.|.|..      .||.:..       :..||.:.|.:  |:||....|...:..
Yeast   142 NTDDQAPVAIKAIIKKGISSDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQESA 206

  Fly   546 TNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLV---- 606
            ...|||.|.|:||::||.|.|:|.|||:.:|.:|..:..|:.::|.|||||||:||||||.
Yeast   207 NYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIP 271

  Fly   607 ---------KLDEH------GNVLELKLADFGLACEV-NDLLYAVCGTPTYVAPEILLEVGYGLK 655
                     |.||.      |.:..:||.|||||.:: |:.....|||..|||.|:.....|.:|
Yeast   272 FYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNTAKTPCGTIEYVASEVFTSKRYSMK 336

  Fly   656 IDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADP 720
            :|:|:.|.:|:.||||:|||.  :..::.|...|..|.|||..|:|.:|..|.::.:.::|:.||
Yeast   337 VDMWSIGCVLFTLLCGYPPFY--EKNEKTLLKKISRGDYEFLAPWWDNISSGAKNAVTHLLEVDP 399

  Fly   721 DVRFTSEDILDHSW 734
            :.|:..:|.|:..|
Yeast   400 NKRYDIDDFLNDPW 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711	4/12 (33%)
		PKc_like	477..734	CDD:304357	103/293 (35%)
		S_TKc	477..734	CDD:214567	103/293 (35%)
RCK1	NP_011357.1	STKc_RCK1-like	119..414	CDD:270998	104/297 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900