Protein Alignment CG17528 and RCK2

DIOPT Version :10

• Sequence 1: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: NP_013349.1
• Gene: RCK2 / 850950
• SGDID: S000004238
• Length: 610
• Species: Saccharomyces cerevisiae
• Alignment Length: 503
• Identity: 130/503 - (25%)
• Similarity: 217/503 - (43%)
• Gaps: 146/503 - (29%)

  Fly   320 SGTKPRRIMRLLLNKRNS---------PSF---DHVLTAITQ--VVRLDTGYVRKVFTLSGIPVV 370
            |||..:.:.::..:.:.|         ||.   ||.:.::|.  |..:|
Yeast    33 SGTNNKDVSQITSSPKKSFQDKNIVQYPSVVADDHHMKSLTDELVTTID---------------- 81

  Fly   371 RLSDFFGSDDVFFAYGTERINT-----AEDFKLEAEEQRAINVIRKTMRTTGTTCKGPKPKMPIK 430
              ||...||::    .||.:.|     |.|....:|.|.:.:
Yeast    82 --SDSSPSDNI----TTENVETVTSVPAIDVHESSEGQLSSD----------------------- 117

  Fly   431 SKKVYPPLVDSE----------PFKAETTPEDDRHAALLTSTGMEINELPSNIRNTYSLGRIIGD 485
                  ||:..|          ..:.::|.:|:....:...:.:|..||..     |.|...||:
Yeast   118 ------PLISDESLSEQSEIISDIQDDSTDDDNMEDEIPEKSFLEQKELIG-----YKLINKIGE 171

  Fly   486 GNFAIVFK-IKHRQTGHSY--------ALKIIDK-----------NKCKGKE-------HYIDAE 523
            |.|:.||: |..:.:.:.:        |:|:|.|           .|.|||:       ..:..|
Yeast   172 GAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKE 236

  Fly   524 VRVMKKLNH--PHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAM 586
            |.:.|.::.  ..|::.|...:.::..|::.|.::||::|..|.::|.|||:.||.:|:.|..|:
Yeast   237 VALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAV 301

  Fly   587 TYLHSMGIVHRDIKPENLL---------------------VKLDE--------HGNVLELKLADF 622
            .::||:|:|||||||||||                     .|.||        .|.:..:|||||
Yeast   302 KHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADF 366

  Fly   623 GLACEV-NDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLF 686
            ||:.:: :......|||..|.|||::.:..|.:|:|:|..|.:||.:|||||||.  |.:.:.|.
Yeast   367 GLSKQIFSKNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFY--DEKIDTLT 429

  Fly   687 DAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSW 734
            :.|..|.|.|..|:|.:|..|.::.:|.:|:.:|..|:..:..||..|
Yeast   430 EKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPW 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX1	156..239	CDD:340526
		Ubl1_cv_Nsp3_N-like	309..392	CDD:475130	17/85 (20%)
		Protein Kinases, catalytic domain	477..734	CDD:473864	99/315 (31%)
RCK2	NP_013349.1	STKc_RCK1-like	161..478	CDD:270998	100/324 (31%)