Protein Alignment CG17528 and Dclk1

DIOPT Version :10

• Sequence 1: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: XP_038959175.1
• Gene: Dclk1 / 83825
• RGDID: 68437
• Length: 756
• Species: Rattus norvegicus
• Alignment Length: 668
• Identity: 271/668 - (40%)
• Similarity: 376/668 - (56%)
• Gaps: 99/668 - (14%)

  Fly   134 LSNTPTADH------IKKRIPSSRTPTRKALRIKFYRNGDRFYPGITIPVSNERYRSFERLFEDL 192
            ::..|:..|      .:.|...:.:..:||.:::|||||||::.||...:|.:|:||||.|..||
  Rat    27 VNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADL 91

  Fly   193 TRLLEENVKIPGAVRTIYNLCG-KKITSLDELEDGQSYVCSCNNENFKKVEYNTGSQPLSNLPLS 256
            ||.|.:||.:|..|||||.:.| |||:|||:|.:|:||||. :.|.|||:||.....|
  Rat    92 TRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLVEGESYVCG-SIEPFKKLEYTKNVNP------- 148

  Fly   257 NSRSNSHRLAKCRPSSPLKNGLLAGSSPFPACGGGTGNGSPLIASRLSDRVTVVHPRIVTLIRSG 321
            |...|....:..|..|.|                .|..|.|   |.:.:....:.|::||:||||
  Rat   149 NWSVNVKTTSASRAVSSL----------------ATAKGGP---SEVRENKDFIRPKLVTIIRSG 194

  Fly   322 TKPRRIMRLLLNKRNSPSFDHVLTAITQVVRLDTGYVRKVFTLSGIPVVRLSDFFGSDDVFFAYG 386
            .|||:.:|:||||:.:.||:.|||.||..::||:|.|::::||.|..|:.|.||||.||:|.|.|
  Rat   195 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACG 259

  Fly   387 TERINTAEDFKLEAEEQRAINVIRKTMRT-------TGTTCKGPKPKMPIKS------------K 432
            .|:....:||.|:..|.|   |::.|..|       .||| |.|.|....||            .
  Rat   260 PEKFRYQDDFLLDESECR---VVKSTSYTKIASASRRGTT-KSPGPSRRSKSPASTSSVNGTPGS 320

  Fly   433 KVYPPLVDSEPFKAETTPED------DRHAALLTS-------TGMEIN----------------- 467
            ::..|.....|..:.|:|..      .:|....||       :.|:.|
  Rat   321 QLSTPRSGKSPSPSPTSPGSLRKQRISQHGGSSTSLSSTKVCSSMDENDGPGEGDELGRRHSLQR 385

  Fly   468 -----------ELPSNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYID 521
                       ::|:.|...|.:||.|||||||:|.:...|.|...||||||.|:||:||||.|.
  Rat   386 GWRREESDEGFQIPATITERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQ 450

  Fly   522 AEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAM 586
            .||.:::::.||:|:.||..:|..|.:|||:|.|.|||||||||..::::|..:..|:.:|.:|:
  Rat   451 NEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAI 515

  Fly   587 TYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVNDLLYAVCGTPTYVAPEILLEVG 651
            .||||:.|||||||||||||...:.|: ..|||.|||||..|:..||.||||||||||||:.|.|
  Rat   516 KYLHSLNIVHRDIKPENLLVYEHQDGS-KSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETG 579

  Fly   652 YGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANML 716
            ||||:|:||||:|.||||||||||....:.||.|||.|:.|..:||.|||.::.|..::||..||
  Rat   580 YGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMML 644

  Fly   717 QADPDVRFTSEDILDHSW 734
            ..:.|.||::..:|:|.|
  Rat   645 LVNVDQRFSAVQVLEHPW 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX1	156..239	CDD:340526	45/83 (54%)
		Ubl1_cv_Nsp3_N-like	309..392	CDD:475130	41/82 (50%)
		Protein Kinases, catalytic domain	477..734	CDD:473864	139/256 (54%)
Dclk1	XP_038959175.1	DCX1_DCLK1	55..143	CDD:340660	49/88 (56%)
		DCX2	182..265	CDD:340589	41/82 (50%)
		STKc_DCKL1	399..666	CDD:271085	142/265 (54%)