DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and CRK3

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_182193.1	Gene:	CRK3 / 819282	AraportID:	AT2G46700	Length:	595	Species:	Arabidopsis thaliana

Alignment Length:	371	Identity:	100/371 - (26%)
Similarity:	160/371 - (43%)	Gaps:	61/371 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   414 RTTGTTCKGPKP---KMPIKSKKVYPPLVDSEPFKAET----------TPEDDRH--AALLTSTG 463
            :.|......|.|   ..|..|....|..|...|.:..|          .|...:|  |:|:...|
plant    45 KNTPARSSNPSPWPSPFPHGSASPLPSGVSPSPARTSTPRRFFRRPFPPPSPAKHIKASLIKRLG 109

  Fly   464 MEINELP--------------------SNIRNTYSLGRIIGDGNFAIVFKIKHRQTG-------- 500
            ::..|.|                    .|....|.||:.:|.|:|.      |..:|
plant   110 VKPKEGPIPEERGTEPEQSLDKSFGYGKNFGAKYELGKEVGRGHFG------HTCSGRGKKGDIK 168

  Fly   501 -HSYALKIIDKNKCKGKEHYIDA--EVRVMKKLN-HPHIISLILSVDQNTNMYLVLEYVSGGDLF 561
             |..|:|||.|.|........|.  ||:::|.|: |.::|....:.:...|:|:|:|...||:|.
plant   169 DHPIAVKIISKAKMTTAIAIEDVRREVKLLKSLSGHKYLIKYYDACEDANNVYIVMELCDGGELL 233

  Fly   562 DAI-TQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLA 625
            |.| .:..::.|:.::.::..:...:::.|..|:||||:||||.|.......:  :|||.||||:
plant   234 DRILARGGKYPEDDAKAIVVQILTVVSFCHLQGVVHRDLKPENFLFTSSREDS--DLKLIDFGLS 296

  Fly   626 --CEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDA 688
              ...::.|..:.|:..|||||: |...|.|:.|:|:.|:|.||||||..||.|  ..:..:|..
plant   297 DFIRPDERLNDIVGSAYYVAPEV-LHRSYSLEADIWSIGVITYILLCGSRPFWA--RTESGIFRT 358

  Fly   689 IISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSW 734
            ::.....:.|..|.......:|.:..:|..|...|.::...|.|.|
plant   359 VLRTEPNYDDVPWPSCSSEGKDFVKRLLNKDYRKRMSAVQALTHPW 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	82/271 (30%)
		S_TKc	477..734	CDD:214567	82/271 (30%)
CRK3	NP_182193.1	STKc_CAMK	142..404	CDD:270687	82/272 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910