Protein Alignment CG17528 and CAMK4

DIOPT Version :10

• Sequence 1: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: NP_001735.1
• Gene: CAMK4 / 814
• HGNCID: 1464
• Length: 473
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 103/261 - (39%)
• Similarity: 148/261 - (56%)
• Gaps: 8/261 - (3%)

  Fly   483 IGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTN 547
            :|.|..:||::.|.:.|...||||::.|...|   ..:..|:.|:.:|:||:||.|....:..|.
Human    52 LGRGATSIVYRCKQKGTQKPYALKVLKKTVDK---KIVRTEIGVLLRLSHPNIIKLKEIFETPTE 113

  Fly   548 MYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHG 612
            :.||||.|:||:|||.|.:...:||..:...::.:..|:.|||..||||||:||||||.......
Human   114 ISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPD 178

  Fly   613 NVLELKLADFGLA--CEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPF 675
              ..||:|||||:  .|...|:..|||||.|.|||||....||.::|:|:.|||.|||||||.||
Human   179 --APLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPF 241

  Fly   676 VAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSWTIGNKG 740
            . .:...:.:|..|::..|.|..|:|.::....:||:..::..||..|.|:...|.|.|..|...
Human   242 Y-DERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAA 305

  Fly   741 N 741
            |
Human   306 N 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX1	156..239	CDD:340526
		Ubl1_cv_Nsp3_N-like	309..392	CDD:475130
		Protein Kinases, catalytic domain	477..734	CDD:473864	100/252 (40%)
CAMK4	NP_001735.1	STKc_CaMKIV	42..335	CDD:270987	103/261 (39%)
		Autoinhibitory domain	305..321		1/2 (50%)
		PP2A-binding	306..323		1/1 (100%)
		Calmodulin-binding. /evidence=ECO:0000255	322..341
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	445..473