DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and stk17al

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_001071197.1	Gene:	stk17al / 777621	ZFINID:	ZDB-GENE-061103-427	Length:	358	Species:	Danio rerio

Alignment Length:	296	Identity:	89/296 - (30%)
Similarity:	150/296 - (50%)	Gaps:	31/296 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   458 LLTSTGMEINELPSNIR-----NTYSL-GRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNK---- 512
            ::...|| :.::.:.||     |.|.| ||.:|.|.||:|.|...:.||..:|.|.:.|.:
Zfish     1 MMNRNGM-VTKIRTRIRTDPFKNNYDLVGRELGRGKFAVVKKCVEKTTGKEHAAKFLRKRRKGQD 64

  Fly   513 CKGKEHYIDAEVRVMKKLN-HPHIISLILSVDQNTNMYLVLEYVSGGDLFD--AITQVTRFSENQ 574
            |:|.   |..|:.|::... :|:::.|....:..:.:.||||..:||::|:  .......|:|..
Zfish    65 CRGD---ILNEIAVLESAEANPYVVGLHEVYETTSEIILVLECAAGGEIFNQCVADNDEAFTEKD 126

  Fly   575 SRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVNDL--LYAVCG 637
            ...:.|.:...::.||...|||.|:||:|:|  |.....:.::::.||||:..|:.:  :..:.|
Zfish   127 VIRLARQILMGVSCLHQNNIVHLDLKPQNIL--LTSAQPLGDIRIVDFGLSRRVDSVSEVREILG 189

  Fly   638 TPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWS 702
            ||.|||||||.........|:|:.|::.|::|.|..||:..:.|:..|      .|.:....|..
Zfish   190 TPEYVAPEILDYEPISTATDMWSIGVLTYVMLTGESPFLGEEKQETFL------NISQVNVDYSQ 248

  Fly   703 DIGDGVRDLIANMLQA----DPDVRFTSEDILDHSW 734
            |:..|:.||..|.:|:    :|..|.|.|..|:|||
Zfish   249 DVFQGISDLAVNFIQSLLIKNPRKRSTVEQCLNHSW 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	82/270 (30%)
		S_TKc	477..734	CDD:214567	82/270 (30%)
stk17al	NP_001071197.1	PKc_like	16..285	CDD:304357	86/280 (31%)
stk17al	NP_001071197.1	S_TKc	27..285	CDD:214567	82/269 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900