DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and uhmk1

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_001070127.1	Gene:	uhmk1 / 767721	ZFINID:	ZDB-GENE-060929-1014	Length:	410	Species:	Danio rerio

Alignment Length:	277	Identity:	77/277 - (27%)
Similarity:	127/277 - (45%)	Gaps:	45/277 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   483 IGDGNFAIVFKIKH-RQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKL-NHPHIISLILSVDQN 545
            :|.|..|.|:::.. |.|.   |:|....:...|...|: .|..|::|: .|.:|::| ..:..|
Zfish    30 LGQGVSASVYRVSSGRATS---AVKEFQVDPQGGDYGYL-KESSVLEKIQGHKNIVTL-YGMFTN 89

  Fly   546 TNMYLVLEYVSGGDLFD-AITQVTRFSENQSRIM--IRHLG----AAMTYLHSMGIVHRDIKPEN 603
            .|.:.|..:....:|.| :::::...:.||...|  |:|..    .|:|:||..|.||.|:||.|
Zfish    90 HNPFGVATHCLLLELLDVSVSELLVRASNQGHSMWLIQHCARDVLEALTFLHREGFVHADLKPRN 154

  Fly   604 LLVKLDEHGNVLELKLADFGLACEV--NDLLYAVCGTPTYVAPEILL-----------EVGYGLK 655
            :|...|:..    .||.||||:.:.  .|:.|  ..|..|.|||..|           :.|....
Zfish   155 VLWSADDEC----FKLIDFGLSFKEGHQDVKY--IQTDGYRAPEAELQNSLAQAGVESDSGCTTA 213

  Fly   656 IDVWAAGIILYILLCGFPPFVAPDNQQ-EPLFDAIISGIYE-----FPD-PYWSDIGDGVRDLIA 713
            :|:|:.||:|..:..|........:|: :....||:..|:.     :|. |.:.     :||||.
Zfish   214 VDLWSLGIVLLEMYSGMKLKETVKSQEWKDNSSAIVDHIFSSNALVYPAIPVFH-----LRDLIK 273

  Fly   714 NMLQADPDVRFTSEDIL 730
            :||..||.:|.|::..|
Zfish   274 SMLHNDPKLRSTAKAAL 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	77/277 (28%)
		S_TKc	477..734	CDD:214567	77/277 (28%)
uhmk1	NP_001070127.1	STKc_KIS	23..299	CDD:270922	77/277 (28%)
		S_TKc	24..295	CDD:214567	77/277 (28%)
		RRM_UHMK1	309..396	CDD:240911
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900