Protein Alignment CG17528 and dclk1

DIOPT Version :10

• Sequence 1: NP_001036462.1
• Gene: CG17528 / 3355134
• FlyBaseID: FBgn0261387
• Length: 748
• Species: Drosophila melanogaster
• Sequence 2: XP_012812605.1
• Gene: dclk1 / 733926
• XenbaseID: XB-GENE-960590
• Length: 753
• Species: Xenopus tropicalis
• Alignment Length: 664
• Identity: 270/664 - (40%)
• Similarity: 380/664 - (57%)
• Gaps: 88/664 - (13%)

  Fly   128 ASGSACLSNTPTADHIKKRIPSSRTPTRKALRIKFYRNGDRFYPGITIPVSNERYRSFERLFEDL 192
            |:|....:::......:.|...:.:..:||.:::|||||||::.||...:|.:|:||||.|..||
 Frog    27 ANGLPSPTHSAHCSFYRTRTLQALSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADL 91

  Fly   193 TRLLEENVKIPGAVRTIYNLCG-KKITSLDELEDGQSYVCSCNNENFKKVEYNTGSQPLSNLPLS 256
            ||.|.:||.:|..|||||.:.| |||||||:|.:|:||||. :.|.|||::|.....|
 Frog    92 TRTLSDNVNLPQGVRTIYTVDGSKKITSLDQLVEGESYVCG-SIEPFKKLDYTKNVNP------- 148

  Fly   257 NSRSNSHRLAKCRPSSPLKNGLLAGSSPFPACGGGTGNGSPLIASRLSDRVTVVHPRIVTLIRSG 321
            |...|....|..|.:.||       ::|..:...|..|..            .:.|::||:||||
 Frog   149 NWSVNVKTTAAPRSAQPL-------AAPKQSFSEGRENKD------------FIRPKLVTIIRSG 194

  Fly   322 TKPRRIMRLLLNKRNSPSFDHVLTAITQVVRLDTGYVRKVFTLSGIPVVRLSDFFGSDDVFFAYG 386
            .|||:.:|:||||:.:.||:.|||.||..::||:|.|::::||.|..|:.|.||||.||:|.|.|
 Frog   195 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVLCLQDFFGDDDIFIACG 259

  Fly   387 TERINTAEDFKLEAEEQRAINVIRKTMRT------TGTTCKGPKPKMPIKS-------------- 431
            .|:....:||.|:..|.|   |::.|..|      ..:|.|.|.|....||
 Frog   260 PEKFRYQDDFLLDESECR---VLKSTSYTKLPGVPRRSTTKSPGPSRRSKSPASTSSGVTCRLSD 321

  Fly   432 -----------KKVYPPLVDSEPFKAETTP------EDDRHAALLTS-------TGMEINEL--- 469
                       .::..|.....|..:.|:|      ...:|:...||       :.|:.:::
 Frog   322 FHAWEVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRGSQHSGSSTSLASTKVCSSMDESDIVVE 386

  Fly   470 ---------PSNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVR 525
                     |.:|...|.:||.|||||||||.:...|.||..||||||:|:||:||||.|..||.
 Frog   387 DIMDEGFQVPVSISERYKVGRTIGDGNFAIVKECIERSTGREYALKIINKSKCRGKEHMIQNEVS 451

  Fly   526 VMKKLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLH 590
            :::::.||:|:.||..:|..:.:|||:|.|.|||||||||...:::|..:..|:.:|.:|:.|||
 Frog   452 ILRRVKHPNIVLLIEEMDMPSELYLVMELVKGGDLFDAITSTNKYTERDANGMLYNLMSAIKYLH 516

  Fly   591 SMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVNDLLYAVCGTPTYVAPEILLEVGYGLK 655
            |:.|||||||||||||...:.|: ..|||.|||||..|:..||.||||||||||||:.|.|||||
 Frog   517 SLNIVHRDIKPENLLVYEHQDGS-KSLKLGDFGLATVVDGPLYTVCGTPTYVAPEIIAETGYGLK 580

  Fly   656 IDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADP 720
            :|:||||:|.||||||||||....:.||.|||.|:.|..:||.|||.::.|..::||..|||.|.
 Frog   581 VDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGHMDFPSPYWDNVSDSAKELITMMLQVDV 645

  Fly   721 DVRFTSEDILDHSW 734
            |.|:::..:|:|.|
 Frog   646 DQRYSALKVLEHPW 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX1	156..239	CDD:340526	46/83 (55%)
		Ubl1_cv_Nsp3_N-like	309..392	CDD:475130	41/82 (50%)
		Protein Kinases, catalytic domain	477..734	CDD:473864	141/256 (55%)
dclk1	XP_012812605.1	DCX1_DCLK1	55..143	CDD:340660	49/88 (56%)
		DCX2	182..265	CDD:340589	41/82 (50%)
		STKc_DCKL1	396..663	CDD:271085	144/265 (54%)