DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and Stk33

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	XP_008758045.2	Gene:	Stk33 / 690861	RGDID:	1590972	Length:	508	Species:	Rattus norvegicus

Alignment Length:	387	Identity:	123/387 - (31%)
Similarity:	203/387 - (52%)	Gaps:	50/387 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   365 SGIPVVRLS--DFFGSDDVFFAYGTER-INTAEDFKLEAEEQRAINVIRKTMRTTGTTCKGPKPK 426
            |.:.||.:|  ...||.|:|.:...:: .|.:.:..|:....|..||.||:.::..........|
  Rat    32 SPVMVVEMSQTSSIGSIDIFTSQERKKERNASRESSLKDLSTRTSNVERKSSQSQRNRSNVTGGK 96

  Fly   427 MPIKSKKVYPPLVDSEPFKAETTPEDDRHAALLTSTGMEINELPSNIRNTYSLGRIIGDGNFAIV 491
            :|                          |..:  ..|..|.|.       |:.|||:|.|:|.:|
  Rat    97 VP--------------------------HIRM--DNGASIEEF-------YTFGRILGQGSFGMV 126

  Fly   492 FKIKHRQTGHSYALKIIDKNKC-KGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYV 555
            .:...::||..:|:|.::|.|. ......::.||.::|.:.|.|||.|....:....||||:|..
  Rat   127 IEATDKETGAKWAIKKVNKEKAGSSAVKLLEREVNILKTVKHQHIIHLEQVFESPQKMYLVMELC 191

  Fly   556 SGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVK---LDEHGNV-LE 616
            ..|:|.:.:.|...|||:::|::|:.|.:|:.||||..|||||:|.||::||   :|::..: |.
  Rat   192 EDGELKEVLDQRGHFSESETRLIIQSLASAIAYLHSKDIVHRDLKLENIMVKSSFIDDNNEMNLN 256

  Fly   617 LKLADFGLACEVN-----DLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFV 676
            :|::|||||.:.:     .::...||||.|:|||::....|..:.|:|:.|:|:||||||.|||:
  Rat   257 IKVSDFGLAVQKHGSRSESMMQTTCGTPIYMAPEVINAHDYSQQCDIWSIGVIMYILLCGEPPFL 321

  Fly   677 APDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSWTIGN 738
            |  |.:|.||:.|..|..:|.||.|..:.|..:..:..:::.||..|.|::::||:.|..||
  Rat   322 A--NSEEKLFELIRKGELQFQDPVWDSVSDSAKSALKQLMKVDPAHRITAKELLDNQWLTGN 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711	9/33 (27%)
		PKc_like	477..734	CDD:304357	99/266 (37%)
		S_TKc	477..734	CDD:214567	99/266 (37%)
Stk33	XP_008758045.2	PKc_like	110..378	CDD:419665	100/276 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820