DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and dapk2a

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_001116536.2	Gene:	dapk2a / 571352	ZFINID:	ZDB-GENE-080402-8	Length:	484	Species:	Danio rerio

Alignment Length:	278	Identity:	94/278 - (33%)
Similarity:	160/278 - (57%)	Gaps:	12/278 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   473 IRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGK-----EHYIDAEVRVMKKLNH 532
            :.:.:.:|..:|.|.||||.:.:.:.:|..:|.|.|.|.:....     ...|:.||.::::::|
Zfish     9 VEDFFEIGEELGSGQFAIVKQCREKSSGRDFAAKFIKKRQSNASRRGVLREEIEREVNILQQIHH 73

  Fly   533 PHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHR 597
            |:|:.|....:..|::.|:||.||||:|||.:.|....||.::...|:.:...:.||||..|.|.
Zfish    74 PNIVMLHDVFENKTDVVLILELVSGGELFDFLAQKESLSEEEATQFIKQILEGVHYLHSRNIAHF 138

  Fly   598 DIKPENLLVKLDEHGNVLELKLADFGLACEVND--LLYAVCGTPTYVAPEILLEVGYGLKIDVWA 660
            |:||||::: ||::..:..:||.|||||.::.:  ....:.|||.:|||||:.....||:.|:|:
Zfish   139 DLKPENIML-LDKNAPLPRIKLIDFGLAHKIAEGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWS 202

  Fly   661 AGIILYILLCGFPPFVAPDNQQEPLFDAIISGI-YEFPDPYWSDIGDGVRDLIANMLQADPDVRF 724
            .|:|.||||.|..||:. :.:|:.|.:  ||.: |||.|.::....:..::.|..:|:.|...|.
Zfish   203 VGVITYILLSGASPFLG-ETKQDTLGN--ISAMNYEFDDEFFGHTSELAKNFIRQLLEKDTKKRL 264

  Fly   725 TSEDILDHSWTIGNKGNE 742
            |.:|.|:|:|...|:..|
Zfish   265 TIQDALNHAWIKSNEHKE 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	91/264 (34%)
		S_TKc	477..734	CDD:214567	91/264 (34%)
dapk2a	NP_001116536.2	PKc_like	7..275	CDD:304357	91/269 (34%)
dapk2a	NP_001116536.2	S_TKc	13..275	CDD:214567	91/265 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810