DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and pnck

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	XP_021334045.1	Gene:	pnck / 567480	ZFINID:	ZDB-GENE-081105-127	Length:	333	Species:	Danio rerio

Alignment Length:	269	Identity:	107/269 - (39%)
Similarity:	163/269 - (60%)	Gaps:	9/269 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   472 NIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHII 536
            :|...|.|...:|:|:|:.|...:||.|....|:|.|.|...||||..::.||.|::::||.:|:
Zfish    12 DINAVYELKEKLGEGSFSEVRVAQHRCTQKLVAVKCIRKRALKGKESMLENEVAVLRRINHENIV 76

  Fly   537 SLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKP 601
            ||..:.:..|.:|||:..::||:|.:.|.:...::|..:..:|..:..|:.|||.:|:||||:||
Zfish    77 SLEETFETPTKLYLVMTLLTGGELLNRILERGSYTEKDASRVIYQVLQAVKYLHQLGVVHRDLKP 141

  Fly   602 ENLLVK--LDEHGNVLELKLADFGLA-CEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGI 663
            |||:.:  |::.    ::.::||||: .|....|...||||.|||||:|.:..||.::|:||.|:
Zfish   142 ENLIFETPLEDS----KIVISDFGLSKMEEQGALSTACGTPAYVAPELLQQKTYGKEVDLWAIGV 202

  Fly   664 ILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSED 728
            |.:|||||:|||.  |:....|:..||...|||..|||:||.|..:|.|.::||.||..||..|.
Zfish   203 ITFILLCGYPPFY--DDNDTQLYKLIIKAEYEFDSPYWNDISDSAKDFIVHLLQKDPAKRFNCEQ 265

  Fly   729 ILDHSWTIG 737
            ...|.|..|
Zfish   266 ASQHPWISG 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	104/259 (40%)
		S_TKc	477..734	CDD:214567	104/259 (40%)
pnck	XP_021334045.1	PKc_like	13..289	CDD:328722	107/268 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820