DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and stk33

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_001038554.2	Gene:	stk33 / 565828	ZFINID:	ZDB-GENE-040724-242	Length:	500	Species:	Danio rerio

Alignment Length:	349	Identity:	119/349 - (34%)
Similarity:	182/349 - (52%)	Gaps:	48/349 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   413 MRTTGTTCKGPKPKMPIK-------SKKVYPPLVDSEPFKAETTPEDDRHAALLTSTGMEINELP 470
            |..|.|...|.:.||..:       .|||           ..|..||:
Zfish     5 MEMTHTNVPGAEKKMACQWTRTNSAEKKV-----------PHTRIEDE----------------- 41

  Fly   471 SNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKC--KGKEHYIDAEVRVMKKLNHP 533
            |:|:..||.||.:|.|:|.:|.:..|.:|...:|:|.::|.|.  .|.:| ::.||.:||::.|.
Zfish    42 SSIQKIYSFGRKLGQGSFGVVCEATHIETQRKWAIKKVNKEKAGTSGVKH-LEREVSIMKQVKHE 105

  Fly   534 HIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRD 598
            |||.|....:....||||.|...||||.|.:.:...|:|.::|.:|:.|..|:.|||...|||||
Zfish   106 HIIHLEEVFETPKRMYLVTELCEGGDLKDLLQKNKHFTEEETRHIIKSLSEAIVYLHKKDIVHRD 170

  Fly   599 IKPENLLVKLDEHGN---VLELKLADFGLACE-----VNDLLYAVCGTPTYVAPEILLEVGYGLK 655
            :|.||:|||....||   ::.:|:.||||:.:     ..::|.|.||||.|:|||::....|..:
Zfish   171 LKLENILVKSCHQGNDNDMVNIKVTDFGLSVQKGGVGSENMLQATCGTPIYMAPEVVNGHQYSQQ 235

  Fly   656 IDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADP 720
            .|:|:.|:|:|:||||.|||  ..:.:|.|.:.|:.|...|..|.|:.|.|..:::|..:|:.||
Zfish   236 CDLWSIGVIMYMLLCGEPPF--GSSSKERLSEMIMKGELTFSGPVWNTISDAAKNVIRCLLKVDP 298

  Fly   721 DVRFTSEDILDHSWTIGNKGNECT 744
            ..|.|:.::||:.|..|:.....|
Zfish   299 AHRITANELLDNPWISGDTSTAVT 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	102/266 (38%)
		S_TKc	477..734	CDD:214567	102/266 (38%)
stk33	NP_001038554.2	PKc_like	46..313	CDD:304357	102/269 (38%)
stk33	NP_001038554.2	S_TKc	48..313	CDD:214567	102/267 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820