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Protein Alignment CG17528 and mapkapk2b

DIOPT Version :10

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	NP_001095273.1	Gene:	mapkapk2b / 557648	ZFINID:	ZDB-GENE-071018-1	Length:	397	Species:	Danio rerio

Alignment Length:	366	Identity:	115/366 - (31%)
Similarity:	170/366 - (46%)	Gaps:	82/366 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   391 NTAE----DFKLEAE-EQRAINVIRKTMRTTGTTCKGPKPKMPIKSKKVYPPLVDSEPFKAETTP 450
            ||.:    ||..|.: .|..|||:......        ||.:.||.|      |.:|.:|.
Zfish     4 NTEDKKESDFSSEQQGTQSPINVLLSESVL--------KPTLKIKKK------VITEEYKL---- 50

  Fly   451 EDDRHAALLTSTGMEINELPSNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKG 515
                                        .|:::|.|....|::|..:::|..:|||::..|. ||
Zfish    51 ----------------------------AGQVLGIGINGKVWEIFQKKSGRHFALKMLRDNP-KG 86

  Fly   516 KEHYIDAEVRV-MKKLNHPHIISLILSVDQNTNMY-------LVLEYVSGGDLFDAITQVTR--- 569
            :.     ||.: .:..:.|.|:.:   .|...|.|       ||:|.:.||:||..| |..|
Zfish    87 RR-----EVELHCRASSCPRIVEI---EDVFENYYQGKKCLLLVMECMEGGELFRHI-QERRDQA 142

  Fly   570 FSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEV--NDLL 632
            |:|.::..::|.:|.|:.:||.:.|.|||:||||||....:..  .:|||.|||.|.|.  |..|
Zfish   143 FTEREASEIMRSIGEAVEFLHGINIAHRDLKPENLLYSSKQPD--AQLKLTDFGFAKETTSNKCL 205

  Fly   633 YAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDA----IISGI 693
            ...|.||.:||||:|....|....|:|:.|:|:||||||:|||.:  |...||...    |.:|.
Zfish   206 TTPCYTPYFVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYS--NNGLPLSPGMRKRIRNGQ 268

  Fly   694 YEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSW 734
            ||||:|.||.:.:..:.||..:|:.||..|.|..:.:...|
Zfish   269 YEFPNPEWSHVSEEAKQLIRQLLKTDPTERMTITEFMKQPW 309

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.