DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17528 and camk1a

DIOPT Version :9

Sequence 1:	NP_001036462.1	Gene:	CG17528 / 3355134	FlyBaseID:	FBgn0261387	Length:	748	Species:	Drosophila melanogaster
Sequence 2:	XP_021332939.1	Gene:	camk1a / 555945	ZFINID:	ZDB-GENE-131120-147	Length:	394	Species:	Danio rerio

Alignment Length:	272	Identity:	108/272 - (39%)
Similarity:	170/272 - (62%)	Gaps:	10/272 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   471 SNIRNTYSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHI 535
            ::|:..|....::|.|.|:.||..:.::|....|:|.|.|...:|||:.|:.|:.|:.::.|.:|
Zfish    15 TDIKENYDFKEVLGTGAFSEVFLAEEKKTQRLVAIKCIPKKALEGKENSIENEIAVLHRIKHENI 79

  Fly   536 ISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIK 600
            :||....:..:::|||::.||||:|||.|.:...::|..:..:||.:..|:.|||.|||||||:|
Zfish    80 VSLEDIFESQSHLYLVMQLVSGGELFDRIVEKGFYTERDASKLIRQILDAVKYLHDMGIVHRDLK 144

  Fly   601 PENLL-VKLDEHGNVLELKLADFGLACEVND---LLYAVCGTPTYVAPEILLEVGYGLKIDVWAA 661
            ||||| ..::|..|::   ::||||: ::.|   ::...||||.|||||:|.:..|...:|.|:.
Zfish   145 PENLLYYSMEEDSNIM---ISDFGLS-KIEDSGSVMSTACGTPGYVAPEVLAQKPYSKAVDCWSI 205

  Fly   662 GIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTS 726
            |:|.||||||:|||.  |.....||:.|:...|||..|||.||.|..:|.|:::::.||.:|:|.
Zfish   206 GVISYILLCGYPPFY--DENDAKLFEQILKAEYEFDSPYWDDISDSAKDFISHLMEKDPSLRYTC 268

  Fly   727 EDILDHSWTIGN 738
            |..|.|.|..|:
Zfish   269 EQALLHPWISGD 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17528	NP_001036462.1	DCX	153..244	CDD:214711
		DCX	308..396	CDD:214711
		PKc_like	477..734	CDD:304357	105/260 (40%)
		S_TKc	477..734	CDD:214567	105/260 (40%)
camk1a	XP_021332939.1	STKc_CaMKI	17..276	CDD:270985	106/264 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920